Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,661 questions · 2,751 findings · 453 reviews

No studies found 593 · 21.6%GRADE not reported 277 · 10.1%Very low 538 · 19.6%Low 712 · 25.9%Moderate 516 · 18.8%High 115 · 4.2%

Epidermal growth factor (EGF), oral spray vs placebo

Interruptions to cancer treatment (radiotherapy breaks longer than two days) · Adults with cancer receiving treatment

Epidermal growth factor (EGF), oral spray showed no clear difference in interruptions to cancer treatment (radiotherapy breaks longer than… compared with placebo; GRADE not reported.

1 finding from 1 review

Intermediate restorative material (IRM) root-end filling vs SuperEBA

Healing - 1 year or longer · People requiring retreatment of periapical lesions (failed root canal therapy)

It is very uncertain whether intermediate restorative material (IRM) root-end filling changes healing - 1 year or longer compared with superEBA (very low certainty).

1 finding from 1 review

Intermediate restorative material (IRM) root-end filling vs Gutta-percha

Healing - 1 year or longer · People requiring retreatment of periapical lesions (failed root canal therapy)

It is very uncertain whether intermediate restorative material (IRM) root-end filling changes healing - 1 year or longer compared with gutta-percha (very low certainty).

1 finding from 1 review

Intervention not reported

Long‐term mortality (> 36 months) · patients with diffuse emphysema

The intervention probably leads to lower long‐term mortality (> 36 months) (moderate certainty).

1 finding from 1 review

Intervention not reported

Quality of life measures (long‐term outcome) · patients with memory deficits following stroke
1 finding from 1 review

Intervention not reported

Subjective memory measures (long‐term outcome) · patients with memory deficits following stroke
1 finding from 1 review

Intervention not reported

Objective memory measures (long‐term outcome) ‐ comprehensive batteries · patients with memory deficits following stroke
1 finding from 1 review

Intervention not reported

Mood measures (long‐term outcome) · patients with memory deficits following stroke
1 finding from 1 review