Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

357 questions · 363 findings · 46 reviews

No studies found 99 · 27.3%GRADE not reported 88 · 24.2%Very low 74 · 20.4%Low 55 · 15.2%Moderate 40 · 11%High 7 · 1.9%

Zinc vs placebo; no treatment

Stunted after 6 months · the promotion of growth and prevention of infections in infants less than six months of age

Zinc supplementation showed no clear difference in stunted after 6 months compared with placebo; no treatment (moderate certainty).

1 finding from 1 review

Zinc vs placebo; no treatment

Wasted after 6 months · the promotion of growth and prevention of infections in infants less than six months of age

Zinc supplementation showed no clear difference in wasted after 6 months compared with placebo; no treatment (low certainty).

1 finding from 1 review

Zinc tape vs magnesium sulphate glycerin

Ulcer healing · ulceration caused by nerve damage in leprosy

It is very uncertain whether zinc tape changes primary outcome: healing of ulcers (number of ulcers healed after 1… compared with magnesium sulphate glycerin (very low certainty).

2 findings from 1 review

Abrasive candy; abrasive candy + 2% propolis; abrasive candy + 0.5% zinc gluconate vs Abrasive candy + 1% propolis + 0.25% zinc

Volatile sulphur compounds (VSC), halimeter · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    Barak 2012 (5-arm RCT) compared abrasive candy, abrasive candy with propolis and abrasive candy with zinc gluconate versus abrasive candy with propolis and zinc; VSC measured by halimeter. We could not use the results…
    1 study
    GRADE not reported

Zinc vs placebo

Taste discrimination improvement · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)
1 finding from 1 review
  • Interventions for managing taste disturbances 2017 · Cochrane All outcomes
    Results: Matson 2003 used zinc sulphate for testing taste discrimination (sip and spit method); the trial did not report the details of the placebo group and thus the results could not be meta-analysed. Not GRADE-rated.
    1 study
    GRADE not reported

Zinc vs placebo

Taste acuity improvement - objective outcome (continuous) - individual taste sensations · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)

Zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… showed no clear difference in taste acuity improvement - objective outcome (continuous) -… compared with placebo; GRADE not reported.

1 finding from 1 review
  • Interventions for managing taste disturbances 2017 · Cochrane All outcomes
    Chronic renal failure
    Results (Mahajan 1980, chronic renal failure; Analysis 1.3): mean difference by taste sensation - salt MD 285 (95% CI 238.75 to 331.25); sweet MD 190 (142.36 to 237.64); sour MD 10 (-16.43 to 36.43); bitter MD 2.40…
    1 study · 22 participants
    GRADE not reported

Zinc vs placebo

Taste acuity improvement - objective outcome (continuous) - taste detection (cross-over trial) · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)

It is very uncertain whether zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… changes taste acuity improvement - objective outcome (continuous) - taste… compared with placebo (very low certainty).

1 finding from 1 review