Question · asked by 1 review

Zinc vs placebo: Taste discrimination improvement

Population
Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)
Intervention
Zinc
Comparison
placebo
Outcome
Taste discrimination improvement

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate, zinc acetate, or polaprezinc) vs Placebo
Taste discrimination improvement · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal…
Interventions for managing taste disturbances (2017) · Cochrane All outcomes
Results: Matson 2003 used zinc sulphate for testing taste discrimination (sip and spit method); the trial did not report the details of the placebo group and thus the results could not be meta-analysed. Not GRADE-rated.1 studyGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for managing taste disturbances
2017 · Cochrane All outcomes
2017-07Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.