Cochrane · systematic review · CD010205
Zinc supplementation for the promotion of growth and prevention of infections in infants less than six months of age
Lassi, ZS, Kurji, J, Oliveira, CSD, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 28.6%Moderate 5 · 71.4%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Zinc supplementation compared to placebo; no treatment for the promotion of growth and prevention of infections in infants less than six months of age
Population: the promotion of growth and prevention of infections in infants less than six months of age
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Length (cm) after 6 months Zinc supplementation vs placebo; no treatment | no estimate extracted | 3 studies · 644 participants | Moderate Downgraded: risk of bias |
Weight (g) after 6 months Zinc supplementation vs placebo; no treatment | no estimate extracted | 3 studies · 644 participants | Low Downgraded: risk of bias |
Weight for age Z‐score after 6 months Zinc supplementation vs placebo; no treatment | no estimate extracted | 3 studies · 955 participants | Moderate Downgraded: risk of bias, imprecision |
Length for age Z‐score after 6 months Zinc supplementation vs placebo; no treatment | no estimate extracted | 3 studies · 955 participants | Moderate Downgraded: risk of bias, imprecision |
Weight for length z‐score after 6 months Zinc supplementation vs placebo; no treatment | no estimate extracted | 3 studies · 955 participants | Moderate Downgraded: risk of bias, imprecision |
Stunted after 6 months Zinc supplementation vs placebo; no treatment | RR 0.82 [0.65, 1.03] | 3 studies · 955 participants | Moderate Downgraded: risk of bias, imprecision |
Wasted after 6 months Zinc supplementation vs placebo; no treatment | RR 0.78 [0.48, 1.26] | 3 studies · 955 participants | Low Downgraded: risk of bias, imprecision |