Single layer gastrointestinal anastomosis showed no clear difference in mortality Odds ratio compared with double layer gastrointestinal anastomosis (low certainty).
Single layer gastrointestinal anastomosis showed no clear difference in major complications Odds ratio compared with double layer gastrointestinal anastomosis (low certainty).
Single layer gastrointestinal anastomosis showed no clear difference in anastomotic leak in high quality trials Odds ratio compared with double layer gastrointestinal anastomosis (moderate certainty).
It is very uncertain whether single layer gastrointestinal anastomosis changes anastomotic leak in poor quality trials Odds ratio compared with double layer gastrointestinal anastomosis (very low certainty).
Single‐immune checkpoint inhibitors (ICIs) probably leads to lower overall survival (OS) compared with chemotherapy (moderate certainty).
Single‐immune checkpoint inhibitors (ICIs) may leads to lower progression‐free survival (PFS) compared with chemotherapy (low certainty).
Single‐immune checkpoint inhibitors (ICIs) may leads to higher overall response rate (ORR) compared with chemotherapy (low certainty).
Single‐immune checkpoint inhibitors (ICIs) may leads to lower adverse Events grade 3‐4 compared with chemotherapy (low certainty).
Single‐immune checkpoint inhibitors (ICIs) may leads to higher QOL‐C30 GHS/QOL (range 0‐100) ‐ change from baseline to week 15 compared with chemotherapy (low certainty).
The review found no eligible studies for this question.
Single herb plus conventional intervention may leads to higher visual acuity (gain of ≥ 2 lines) (end of treatment) compared with conventional intervention (low certainty).
It is very uncertain whether single herb plus conventional intervention changes reduction in microaneurysms compared with conventional intervention (very low certainty).
It is very uncertain whether single herb plus conventional intervention changes observations in retina: reduction in haemorrhages compared with conventional intervention (very low certainty).
Paracetamol (single administration, any dose) may leads to higher adequate pain relief as reported by women compared with placebo (low certainty).
Paracetamol (single administration, any dose) may leads to lower additional pain relief compared with placebo (low certainty).
Paracetamol (single administration, any dose) showed no clear difference in maternal drug adverse effects (nausea) compared with placebo (low certainty).