Findings

What do systematic reviews say?

1,841 questions · 1,893 findings · 109 reviews · Headline outcomes only

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No studies found 546 · 28.8%GRADE not reported 117 · 6.2%Very low 613 · 32.4%Low 473 · 25%Moderate 118 · 6.2%High 26 · 1.4%

Intervention vs no intervention or control intervention (control)

Health‐related quality of life · people with acute hepatitis C infection

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for acute hepatitis C infection 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention vs no intervention or control intervention (control)

Liver transplantation · people with acute hepatitis C infection

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for acute hepatitis C infection 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention vs no intervention or control intervention (control)

Decompensated liver disease · people with acute hepatitis C infection

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for acute hepatitis C infection 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention vs no intervention or control intervention (control)

Cirrhosis · people with acute hepatitis C infection

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for acute hepatitis C infection 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Pharmacological interventions vs placebo

GABA analogue VAS(0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 297 participants
High

Pharmacological interventions vs placebo

Montelukast Duo score (0 to 81) and VAS (0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 87 participants
Moderate

Pharmacological interventions vs placebo

Sertraline VAS(0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 46 participants
Low

Pharmacological interventions vs placebo

Lidocaine Itch relief · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low

Pharmacological interventions vs placebo

Sodium thalidomide Itch relief · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
Very low

Pharmacological interventions vs placebo

Doxepin Itch relief · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
Low

Pharmacological interventions vs placebo

Ondansetron VAS(0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 183 participants
High

Pharmacological interventions vs placebo

Kappa‐opioid agonist VAS(0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 661 participants
High

Pharmacological interventions vs placebo

Mu‐opioid antagonist VAS(0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 62 participants
Low

Pharmacological interventions vs placebo

Nalbuphine VAS(0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 179 participants
Low

Pharmacological interventions vs placebo

Cromolyn VAS(0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Low

Pharmacological interventions vs placebo

Nicotinamide VAS(0 to 5 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

Pharmacological interventions vs placebo

EPO Duo score(0 to 40) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Very low

Pharmacological interventions vs placebo

Cholestyramine 0 to 3 severity scale · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 15 participants
Low

Pharmacological interventions vs placebo

Smoking cessation · young people

It is very uncertain whether pharmacological interventions changes bupropion vs placebo Smoking cessation compared with placebo (very low certainty).

3 findings from 1 review

Tobacco cessation interventions for young people 2017 · Cochrane Headline outcomes only
RR 1.49 [0.55, 4.02]
1 study · 207 participants
Very low
Tobacco cessation interventions for young people 2017 · Cochrane Headline outcomes only
RR 1.05 [0.41, 2.69]
1 study · 211 participants
Very low
Tobacco cessation interventions for young people 2017 · Cochrane Headline outcomes only
RR 1.11 [0.48, 2.58]
2 studies · 385 participants
Very low

Pharmacological interventions vs placebo

Adverse events (control ‐ placebo) · young people

3 findings from 1 review

Tobacco cessation interventions for young people 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 207 participants
Very low
Tobacco cessation interventions for young people 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 211 participants
Very low
Tobacco cessation interventions for young people 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 385 participants
Very low