Findings

What do systematic reviews say?

328 questions · 332 findings · 35 reviews

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No studies found 83 · 25%GRADE not reported 11 · 3.3%Very low 75 · 22.6%Low 105 · 31.6%Moderate 45 · 13.6%High 13 · 3.9%

NSAIDs vs paracetamol

Relief of pain · women with primary dysmenorrhoea

NSAIDs may leads to higher pain relief dichotomous data compared with paracetamol (low certainty).

1 finding from 1 review

Nonsteroidal anti‐inflammatory drugs for dysmenorrhoea 2015 · Cochrane Headline outcomes only
OR 1.89 [1.05, 3.43]
Studies not reported
Low

NSAIDs vs paracetamol

All adverse effects ‐ ibuprofen versus paracetamol · women with primary dysmenorrhoea

It is very uncertain whether NSAIDs changes all adverse effects ‐ ibuprofen versus paracetamol compared with paracetamol (very low certainty).

1 finding from 1 review

Nonsteroidal anti‐inflammatory drugs for dysmenorrhoea 2015 · Cochrane Headline outcomes only
OR 0.85 [0.31, 2.34]
Studies not reported
Very low

Oral NSAIDs vs placebo

Functional disability at 3 months ‐ not measured · Adults with lateral elbow pain

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 292 participants
Low

Oral NSAIDs vs placebo

Withdrawals due to adverse events · Adults with lateral elbow pain

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral NSAIDs vs placebo

Adverse events · Adults with lateral elbow pain

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 292 participants
GRADE not reported

Oral NSAIDs vs glucocorticoid injection

Pain 0 to 100 visual analogue scale and 10‐point Likert scale (lower score = less pain) · Adults with lateral elbow pain

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 126 participants
Very low

Oral NSAIDs vs glucocorticoid injection

Treatment success Fair, good or excellent effectiveness · Adults with lateral elbow pain

It is very uncertain whether oral NSAIDs changes treatment success Fair, good or excellent effectiveness compared with glucocorticoid injection (very low certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
RR 0.74 [0.43, 1.26]
2 studies · 126 participants
Very low

Oral NSAIDs vs glucocorticoid injection

Quality of life · Adults with lateral elbow pain

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral NSAIDs vs glucocorticoid injection

Function/disability 10‐point Likert scale (lower score = less disability) · Adults with lateral elbow pain

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 105 participants
Low

Oral NSAIDs vs glucocorticoid injection

Withdrawals due to adverse events · Adults with lateral elbow pain

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral NSAIDs vs glucocorticoid injection

Adverse events · Adults with lateral elbow pain

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral NSAIDs vs placebo

Pain 0 to 100 visual analogue scale and 10‐point Likert scale (lower score = less pain) · Adults with lateral elbow pain

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 292 participants
Very low

Oral NSAIDs vs placebo

Treatment success Fair, good or excellent effectiveness · Adults with lateral elbow pain

Oral NSAIDs showed no clear difference in treatment success Fair, good or excellent effectiveness compared with placebo (low certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
RR 1.17 [0.82, 1.67]
1 study · 111 participants
Low

Oral NSAIDs vs placebo

Quality of life · Adults with lateral elbow pain

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

COX‐2 NSAIDs vs placebo

BASDAI Scale from 0 to 100 (higher is worse) · patients with axSpA (AS and nr‐axSpA)

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and… 2015 · Cochrane Headline outcomes only
no estimate extracted
193 participants
Moderate

COX‐2 NSAIDs vs placebo

BASFI Scale from 0 to 100 (higher is worse) · patients with axSpA (AS and nr‐axSpA)

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and… 2015 · Cochrane Headline outcomes only
no estimate extracted
349 participants
High

COX‐2 NSAIDs vs placebo

BASMI Scale from 0 to 10 (higher is worse) · patients with axSpA (AS and nr‐axSpA)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

COX‐2 NSAIDs vs placebo

Radiographic progression · patients with axSpA (AS and nr‐axSpA)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

COX‐2 NSAIDs vs placebo

Number of serious adverse events · patients with axSpA (AS and nr‐axSpA)

COX‐2 NSAIDs showed no clear difference in number of serious adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and… 2015 · Cochrane Headline outcomes only
RR 0.92 [0.14, 6.21]
669 participants
Moderate

COX‐2 NSAIDs vs placebo

Pain (short term) WOMAC scale from 0 to 20 points (higher is worse pain). · patients with axSpA (AS and nr‐axSpA)

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and… 2015 · Cochrane Headline outcomes only
no estimate extracted
349 participants
High