Cochrane · systematic review · CD001751

Nonsteroidal anti‐inflammatory drugs for dysmenorrhoea

Marjoribanks, J, Ayeleke, RO, Farquhar, C, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Gynaecology and FertilityAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 25%Low 3 · 75%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

NSAIDs compared to placebo for dysmenorrhoea

Population: women with primary dysmenorrhoea
2 questions
OutcomeEffectEvidenceStatus / GRADE
Pain relief dichotomous data
NSAIDs vs placebo
OR 4.37 [3.76, 5.09]NRLow
Downgraded: risk of bias, imprecision, inconsistency, publication bias
All adverse effects
NSAIDs vs placebo
OR 1.29 [1.11, 1.51]NRLow
Downgraded: risk of bias, imprecision, publication bias

NSAIDs compared to paracetamol for dysmenorrhoea

Population: women with primary dysmenorrhoea
2 questions
OutcomeEffectEvidenceStatus / GRADE
Pain relief dichotomous data
NSAIDs vs paracetamol
OR 1.89 [1.05, 3.43]NRLow
Downgraded: risk of bias, imprecision
All adverse effects ‐ ibuprofen versus paracetamol
NSAIDs vs paracetamol
OR 0.85 [0.31, 2.34]NRVery low
Downgraded: risk of bias, imprecision