Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

159 questions · 169 findings · 22 reviews · Schizophrenia

No studies found 10 · 5.9%GRADE not reported 44 · 26%Very low 25 · 14.8%Low 25 · 14.8%Moderate 60 · 35.5%High 5 · 3%

STANDARD‐LOWER DOSE (greater than or equal to 4‐<6 mg/day) vs ANY DOSE ‐ short term

Leaving the study early: Any reasons ‐ when compared with standard‐higher dose (greater than or equal to 6‐<10 mg/day) · patients with schizophrenia

STANDARD‐LOWER DOSE (greater than or equal to 4‐<6 mg/day) showed no clear difference in leaving the study early: Any reasons ‐ when compared with… compared with ANY DOSE ‐ short term (moderate certainty).

1 finding from 1 review

STANDARD‐LOWER DOSE (greater than or equal to 4‐<6 mg/day) vs ANY DOSE ‐ short term

Leaving the study early: any reason ‐ when compared with high dose ( greater than or equal to 10 mg) · patients with schizophrenia

STANDARD‐LOWER DOSE (greater than or equal to 4‐<6 mg/day) showed no clear difference in leaving the study early: Any reasons ‐ When compared with high dose… compared with ANY DOSE ‐ short term (moderate certainty).

1 finding from 1 review

STANDARD‐LOWER DOSE (greater than or equal to 4‐<6 mg/day) vs ANY DOSE ‐ short term

Global state: No clinically important improvement ‐ global evaluation ‐ when compared with standard‐higher dose (greater than or equal to 6‐<10 mg/day) · patients with schizophrenia

STANDARD‐LOWER DOSE (greater than or equal to 4‐<6 mg/day) showed no clear difference in global state: No clinically important improvement ‐ global… compared with ANY DOSE ‐ short term (moderate certainty).

1 finding from 1 review

Horticultural therapy plus standard care vs usual care

Well‐being and quality of life Personal Wellbeing Index (PWI‐C) . Scale from: 0 to 77 (low = poor) · patients with schizophrenia

It is very uncertain whether horticultural therapy plus standard care changes well‐being and quality of life Personal Wellbeing Index (PWI‐C) .… compared with standard care alone (very low certainty).

1 finding from 1 review

Intervention not reported

Global effect: 1a. Medium‐term ‐ Average end point score on various outcomes ‐ CGI‐severity (low = favourable) ( · schizophrenia
1 finding from 1 review

Intervention not reported

Mental state: 1b. Average end point score on various outcomes‐PANSS (medium‐term) ‐ Medium‐term ‐ PANSS negative end point score (low = favourable) · schizophrenia
1 finding from 1 review

Intervention not reported

Mental state: 1b.Average end point score on various outcomes‐PANSS (medium‐term) ‐ Medium term ‐ PANSS general psychopathology end point score (low = favourable) · schizophrenia
1 finding from 1 review

Intervention not reported

Adverse event: 11a. Short‐term ‐ Average end point score on EPSEs scale (low = favourable) ‐ AIMS · schizophrenia
1 finding from 1 review