End‐stage renal disease · patients with type 2 diabetes mellitus
Intensive glycaemic control showed no clear difference in end‐stage renal disease compared with conventional glycaemic control (moderate certainty).
1 finding from 1 review
Severe hypoglycaemia · patients with type 2 diabetes mellitus
Intensive glycaemic control leads to higher hypoglycaemia ‐ Severe hypoglycaemia compared with conventional glycaemic control (high certainty).
1 finding from 1 review
All‐cause mortality · people at increased risk for developing type 2 diabetes
1 finding from 1 review
Development of type 2 diabetes · people at increased risk for developing type 2 diabetes
It is very uncertain whether summary of findings table for metformin plus intensive diet and… changes incidence of type 2 diabetes mellitus (N) Diagnostic criteria: 2… compared with intensive diet and exercise (very low certainty).
1 finding from 1 review
Serious adverse events · people at increased risk for developing type 2 diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Cardiovascular mortality · people at increased risk for developing type 2 diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Non‐fatal myocardial infarction/stroke · people at increased risk for developing type 2 diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life · people at increased risk for developing type 2 diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Socioeconomic effects Description: direct medical costs per participant · people at increased risk for developing type 2 diabetes
1 finding from 1 review
Continuation of hormonal contraceptive method · Women of reproductive age seeking to avoid pregnancy
It is very uncertain whether intensive counseling changes continuation of hormonal contraceptive method compared with usual family planning care (very low certainty).
1 finding from 1 review
Rate of discontinuation due to menstrual disturbances · Women of reproductive age seeking to avoid pregnancy
Intensive counseling may leads to lower rate of discontinuation due to menstrual disturbances compared with usual family planning care (low certainty).
1 finding from 1 review
Rate of discontinuation due to all other adverse events · Women of reproductive age seeking to avoid pregnancy
Intensive counseling showed no clear difference in rate of discontinuation due to all other adverse events compared with usual family planning care (low certainty).
1 finding from 1 review
Adherence to method use · Women of reproductive age seeking to avoid pregnancy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pregnancy · Women of reproductive age seeking to avoid pregnancy
It is very uncertain whether intensive counseling changes pregnancy compared with usual family planning care (very low certainty).
1 finding from 1 review
Occurrence of CIP/CIM ‐ in the total population randomised · critically ill patients
Intensive insulin therapy may leads to lower occurrence of CIP/CIM ‐ in total population randomised compared with conventional insulin therapy (low certainty).
1 finding from 1 review
Occurrence of CIP/CIM ‐ in screened population · critically ill patients
Intensive insulin therapy probably leads to lower occurrence of CIP/CIM ‐ in screened population compared with conventional insulin therapy (moderate certainty).
1 finding from 1 review
Duration of mechanical ventilation · critically ill patients
1 finding from 1 review
Duration of ICU stay · critically ill patients
1 finding from 1 review
Death ‐ at 30 days after ICU admission, in total population randomised · critically ill patients
Intensive insulin therapy showed no clear difference in death ‐ at 30 days after ICU admission, in total population randomised compared with conventional insulin therapy (high certainty).
1 finding from 1 review
Death ‐ at 180 days after ICU admission, in total population randomised · critically ill patients
Intensive insulin therapy showed no clear difference in death ‐ at 180 days after ICU admission, in total population… compared with conventional insulin therapy (moderate certainty).
1 finding from 1 review