Summary of findings table for metformin plus intensive diet and exercise vs intensive diet and exercise: Development of type 2 diabetes
It is very uncertain whether summary of findings table for metformin plus intensive diet and… changes incidence of type 2 diabetes mellitus (N) Diagnostic criteria: 2… compared with intensive diet and exercise (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Summary of findings table for metformin plus intensive diet and exercise vs intensive diet and exercise Incidence of type 2 diabetes mellitus (N) Diagnostic criteria: 2 trials applied the WHO 1999 criteria (FPG ≥7.0 mmol/L and/or a 2‐hour glucose ≥11.1 mmol/L after a 75 g OGTT) (IDPP‐1 2006; Zhao 2013) · people at increased risk for developing type 2 diabetes It is very uncertain whether summary of findings table for metformin plus intensive diet and… changes incidence of type 2 diabetes mellitus (N) Diagnostic criteria: 2… compared with intensive diet and exercise (very low certainty). Metformin for prevention or delay of type 2 diabetes mellitus and its associated complications in persons at… (2019) · Cochrane Headline outcomes only | RR 0.55 [0.1, 2.92] | 2 studies · 332 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Metformin for prevention or delay of type 2 diabetes mellitus and its associated complications in persons at increased risk for the… 2019 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.