Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

315 questions · 322 findings · 87 reviews · Neonatal

No studies found 47 · 14.6%GRADE not reported 18 · 5.6%Very low 78 · 24.2%Low 105 · 32.6%Moderate 50 · 15.5%High 24 · 7.5%

Surfactant treatment guided by rapid tests for surfactant deficiency vs surfactant therapy provided to preterm infants with respiratory distress syndrome diagnosed on clinical and radiologic criteria

Neonatal mortality · preterm infants at risk of respiratory distress syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Two per cent CHG vs alcohol hand sanitiser (61% alcohol and emollients)

Incidence of bacteriologically confirmed infection (types of infection as specified by study authors) within the first 28 days of life ‐ all infections · Neonates and caregivers

Two per cent CHG probably leads to lower incidence of bacteriologically confirmed infections (types of… compared with alcohol hand sanitiser (61% alcohol and emollients) (moderate certainty).

1 finding from 1 review

Alcohol‐based handrub vs usual care

Incidence of (study author‐defined) suspected infection within the first 28 days of life · Neonates and caregivers

It is very uncertain whether alcohol‐based handrub changes incidence of suspected infections (author‐defined) within the first… compared with usual care (very low certainty).

1 finding from 1 review