Total number of AOM recurrences at 12 months post‐randomisation
1 finding from 1 review
Disease‐specific quality of life
1 finding from 1 review
Proportion of patients who have no AOM recurrences at 6 months post‐randomisation
It is very uncertain whether grommets changes proportion of patients who have no AOM recurrences at 6 months… compared with antibiotic prophylaxis (very low certainty).
1 finding from 1 review
Total number of AOM recurrences at 6 months post‐randomisation
It is very uncertain whether grommets changes total number of AOM recurrences at 6 months post‐randomisation compared with antibiotic prophylaxis (very low certainty).
1 finding from 1 review
Proportion of patients who have no AOM recurrences at 6 months post‐randomisation
It is very uncertain whether grommets changes proportion of patients who have no AOM recurrences at 6 months… compared with placebo medication (very low certainty).
1 finding from 1 review
Intervention not reported
Adverse events ‐ recurrent fever · acute bacterial meningitis
The intervention probably leads to higher adverse events ‐ recurrent fever (moderate certainty).
1 finding from 1 review
Recurrence of symptomatic UTI in children · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment showed no clear difference in recurrence of symptomatic UTI in children compared with placebo or no treatment (low certainty).
1 finding from 1 review
Recurrence of symptomatic UTI in children without VUR · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment showed no clear difference in recurrence of symptomatic UTI in children without VUR compared with placebo or no treatment (low certainty).
1 finding from 1 review
Recurrence of symptomatic UTI in children with VUR · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment showed no clear difference in recurrence of symptomatic UTI in children with VUR compared with placebo or no treatment (low certainty).
1 finding from 1 review
Recurrence of symptomatic UTI in children, in studies with adequate allocation concealment · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment probably leads to lower recurrence of symptomatic UTI in children, in studies with adequate… compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Repeat positive urine culture · children with previous UTI and most do not have a renal tract abnormality such as VUR
It is very uncertain whether antibiotic treatment changes repeat positive urine culture compared with placebo or no treatment (very low certainty).
1 finding from 1 review
All adverse events · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment showed no clear difference in all adverse events compared with placebo or no treatment (low certainty).
1 finding from 1 review
Microbial resistance to prophylactic drug · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment showed no clear difference in microbial resistance to prophylactic drug compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Health‐related quality of life (SNOT‐22) (range 0 to 110) · adult patients who underwent primary endoscopic sinus surgery, with a diagnosis of recurrent acute or chronic rhinosinusitis
1 finding from 1 review
Disease severity, measured by patient‐reported symptom score (VAS) (range 0 to 100) · adult patients who underwent primary endoscopic sinus surgery, with a diagnosis of recurrent acute or chronic rhinosinusitis
1 finding from 1 review
Significant adverse effects: significant bleeding requiring intervention, severe pain, iatrogenic injury · adult patients who underwent primary endoscopic sinus surgery, with a diagnosis of recurrent acute or chronic rhinosinusitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adhesion rate · adult patients who underwent primary endoscopic sinus surgery, with a diagnosis of recurrent acute or chronic rhinosinusitis
Sinonasal debridement may leads to lower adhesion rate compared with no debridement (low certainty).
1 finding from 1 review
Rate of revision surgeries · adult patients who underwent primary endoscopic sinus surgery, with a diagnosis of recurrent acute or chronic rhinosinusitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found