Findings

What do systematic reviews say?

83 questions · 85 findings · 14 reviews

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No studies found 22 · 25.9%GRADE not reported 1 · 1.2%Very low 18 · 21.2%Low 28 · 32.9%Moderate 15 · 17.6%High 1 · 1.2%

Buprenorphine vs clonidine

Withdrawal symptoms · patients with opiate dependent adolescents

1 finding from 1 review

Detoxification treatments for opiate dependent adolescents 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 32 participants
Moderate

Buprenorphine vs clonidine

Initiation of naltrexone treatment Number of participants initiating naltrexone · patients with opiate dependent adolescents

Buprenorphine probably leads to higher initiation of naltrexone treatment Number of participants initiating… compared with clonidine (moderate certainty).

1 finding from 1 review

Detoxification treatments for opiate dependent adolescents 2014 · Cochrane Headline outcomes only
RR 11 [1.58, 76.55]
1 study · 36 participants
Moderate

Desipramine (antidepressant) vs clonidine

ADHD symptoms · Children and adolescents with ADHD

1 finding from 1 review

Tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 68 participants
Very low