Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

127 questions · 128 findings · 15 reviews · Pregnancy and Childbirth

No studies found 19 · 14.8%GRADE not reported 35 · 27.3%Very low 25 · 19.5%Low 29 · 22.7%Moderate 12 · 9.4%High 8 · 6.3%

Cervical cerclage in combination with antibiotics and tocolytics vs cervical cerclage

Preterm birth less than 34 weeks' gestation

It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes preterm birth < 34 completed weeks of pregnancy compared with cervical cerclage alone (very low certainty).

1 finding from 1 review

Antibiotic prophylaxis vs no treatment or placebo

Adverse effects of antibiotics (skin rash) · Women who had normal vaginal births

It is very uncertain whether routine antibiotic prophylaxis changes adverse effects of antibiotics (skin rash) compared with no treatment or placebo (very low certainty).

1 finding from 1 review

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) vs broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all outcomes

B2: Maternal sepsis – an all women · women undergoing caesarean section

It is very uncertain whether antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) changes maternal sepsis compared with broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all… (very low certainty).

1 finding from 1 review

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) vs broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all outcomes

Endometritis · women undergoing caesarean section

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) showed no clear difference in maternal endometritis compared with broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all… (low certainty).

1 finding from 1 review

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) vs broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all outcomes

Wound infection · women undergoing caesarean section

It is very uncertain whether antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) changes maternal wound infection compared with broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all… (very low certainty).

1 finding from 1 review

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) vs broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all outcomes

Maternal urinary tract infection · women undergoing caesarean section

It is very uncertain whether antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) changes maternal urinary tract infection compared with broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all… (very low certainty).

1 finding from 1 review