What do systematic reviews say?

Topical quinolone vs povidone‐iodine

The review found no eligible studies for this question.

• Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical quinolone vs povidone‐iodine

It is very uncertain whether topical antibiotics (quinolones) changes suspected ototoxicity compared with povidone‐iodine (very low certainty).

• Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 40 participants
  Very low

Topical quinolone vs boric acid

Topical antibiotics (quinolones) probably leads to higher resolution of ear discharge (1 to 2 weeks) Quinolones compared with boric acid (moderate certainty).

• Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  RR 1.86 [1.48, 2.35]
  1 study · 411 participants
  Moderate

Topical quinolone vs boric acid

The review found no eligible studies for this question.

• Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics

Antibiotic eardrops (with or without a corticosteroid) probably leads to higher resolution of ear discharge at short‐term compared with oral antibiotics (moderate certainty).

• Interventions for children with ear discharge occurring at least two weeks following grommet (ventilation tube)… 2016 · Cochrane Headline outcomes only
  RR 2.58 [1.27, 5.22]
  1 study · 42 participants
  Moderate

Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics

Antibiotic eardrops (with or without a corticosteroid) showed no clear difference in adverse events compared with oral antibiotics (low certainty).

• Interventions for children with ear discharge occurring at least two weeks following grommet (ventilation tube)… 2016 · Cochrane Headline outcomes only
  RR 0.37 [0.12, 1.09]
  3 studies · 705 participants
  Low

Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics

• Interventions for children with ear discharge occurring at least two weeks following grommet (ventilation tube)… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 153 participants
  Very low

Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics

Antibiotic eardrops (with or without a corticosteroid) probably leads to higher resolution of ear discharge at intermediate‐term compared with oral antibiotics (moderate certainty).

• Interventions for children with ear discharge occurring at least two weeks following grommet (ventilation tube)… 2016 · Cochrane Headline outcomes only
  RR 1.7 [1.38, 2.08]
  1 study · 153 participants
  Moderate

Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics

• Interventions for children with ear discharge occurring at least two weeks following grommet (ventilation tube)… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 232 participants
  Moderate

Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics

Antibiotic eardrops (with or without a corticosteroid) showed no clear difference in tube blockage compared with oral antibiotics (low certainty).

• Interventions for children with ear discharge occurring at least two weeks following grommet (ventilation tube)… 2016 · Cochrane Headline outcomes only
  RR 1.2 [0.33, 4.45]
  2 studies · 121 participants
  Low

Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics

The review found no eligible studies for this question.

• Interventions for children with ear discharge occurring at least two weeks following grommet (ventilation tube)… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics

• Interventions for children with ear discharge occurring at least two weeks following grommet (ventilation tube)… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 153 participants
  Low

Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics

• Interventions for children with ear discharge occurring at least two weeks following grommet (ventilation tube)… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 153 participants
  Low

Topical antibiotics with steroids vs placebo/no treatment

The review found no eligible studies for this question.

• Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical antibiotics with steroids vs placebo/no treatment

• Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 50 participants
  Very low

Topical antibiotics with steroids vs placebo/no treatment

The review found no eligible studies for this question.

• Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical antibiotics with steroids vs placebo/no treatment

• Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 123 participants
  Very low

Topical antibiotics with steroids vs placebo/no treatment

• Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 123 participants
  Very low

Topical antibiotics with steroids vs placebo/no treatment

• Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 173 participants
  Very low

Topical antibiotics with steroids vs placebo/no treatment

• Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 123 participants
  Very low