Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,532 questions · 2,642 findings · 483 reviews · Headline outcomes only

No studies found 534 · 20.2%GRADE not reported 82 · 3.1%Very low 641 · 24.3%Low 807 · 30.5%Moderate 472 · 17.9%High 106 · 4%

Fetal biometry vs maternal glycaemic values

Hypertensive disorders of pregnancy · women with gestational diabetes mellitus and their babies

It is very uncertain whether fetal biometry changes hypertensive disorders of pregnancy (including pre‐eclampsia,… compared with maternal glycaemic values (very low certainty).

1 finding from 1 review

Intervention not reported

Hypotension (within 30 days; as defined by study authors, minimum systolic blood pressure < 90 mmHg or requiring medication) · adults undergoing cardiac surgery under general anaesthesia

The intervention showed no clear difference in hypotension (within 30 days; as defined by study authors, minimum… (low certainty).

1 finding from 1 review

Perioperative beta‐blockers vs placebo or usual care

Hypotension · adults undergoing non‐cardiac surgery under general anaesthesia (to include: low‐risk, medium‐risk, and high‐risk surgeries)

Perioperative beta‐blockers probably leads to higher hypotension (within 30 days; as defined by study authors, minimum… compared with placebo or standard care (moderate certainty).

1 finding from 1 review

Laparoscopic vs open appendectomy

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with suspected appendicitis
3 findings from 1 review

Intervention not reported

Maternal admission to intensive care · pregnant women

The intervention showed no clear difference in maternal admission to intensive care (low certainty).

1 finding from 1 review

Alpha2‐adrenergic agonist vs control

Hypotension (requiring treatment with inotropes or vasopressors during the period of study drug administration) · adults undergoing cardiac surgery

Alpha‐2 adrenergic agonists showed no clear difference in hypotension (requiring treatment with inotropes or vasopressors… compared with control (low certainty).

1 finding from 1 review