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Evidence found and GRADE certainty

1,763 questions · 1,835 findings · 201 reviews · Headline outcomes only

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No studies found 414 · 22.6%GRADE not reported 51 · 2.8%Very low 570 · 31.1%Low 468 · 25.5%Moderate 272 · 14.8%High 60 · 3.3%

Summary of findings table ‐ Structured exercise interventions vs usual care with or without sham interventions

Falls during hospitalisation · acutely hospitalised older medical patients

Summary of findings table ‐ Structured exercise interventions showed no clear difference in falls during hospitalisation compared with usual care with or without sham interventions (low certainty).

1 finding from 1 review

Summary of findings table ‐ Structured exercise interventions vs usual care with or without sham interventions

Medical deterioration during hospitalisation · acutely hospitalised older medical patients

It is very uncertain whether summary of findings table ‐ Structured exercise interventions changes medical deterioration during hospitalisation compared with usual care with or without sham interventions (very low certainty).

1 finding from 1 review

Low‐frequency electroacupuncture vs physical exercise or no intervention

Restored regular menstrual period · polycystic ovarian syndrome

It is very uncertain whether low‐frequency electroacupuncture changes restored regular menstrual period – low‐frequency electroacupuncture… compared with physical exercise or no intervention (very low certainty).

2 findings from 1 review

Metformin vs diet and exercise or another antidiabetic drug

Intensive diet plus exercise · people at increased risk for developing type 2 diabetes
4 findings from 1 review
Show 1 more finding

Metformin vs diet and exercise or another antidiabetic drug

Placebo or diet and exercise · people at increased risk for developing type 2 diabetes
2 findings from 1 review

Metformin vs diet and exercise or another antidiabetic drug

Placebo or diet and exercise Description: SF‐36 to evaluate the health utility index SF‐6D (physical component summaries and mental component summaries) Minimal important difference: difference in scores between groups of at least 3% · people at increased risk for developing type 2 diabetes
1 finding from 1 review

Metformin vs diet and exercise or another antidiabetic drug

Placebo or diet and exercise Diagnostic criteria: 3 trials applied the WHO 1985 criteria (FPG <7.8 mmol/L and 2‐hour glucose ≥7.8 mmol/L and <11.1 mmol/L after a 75 g OGTT) (Fang 2004; Li 1999; Lu 2002). 5 trials applied the WHO 1999 criteria (FPG... · people at increased risk for developing type 2 diabetes

Summary of findings table for metformin probably leads to lower placebo or diet and exercise Diagnostic criteria: 3 trials applied… compared with diet and exercise or another antidiabetic drug (moderate certainty).

1 finding from 1 review

Metformin vs diet and exercise or another antidiabetic drug

Intensive diet plus exercise Diagnostic criteria: 1 trial applied the WHO 1985 criteria (FPG < 7.8 mmol/L and 2‐hour glucose ≥ 7.8 mmol/L and < 11.1 mmol/L) (Fang 2004) · people at increased risk for developing type 2 diabetes

Summary of findings table for metformin showed no clear difference in intensive diet plus exercise Diagnostic criteria: 1 trial applied… compared with diet and exercise or another antidiabetic drug (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Exercise plus usual pharmacological care vs usual pharmacological care alone

Withdrawals due to any reason · systemic lupus erythematosus

It is very uncertain whether summary of findings table ‐ Exercise plus usual pharmacological care changes withdrawals due to any reason compared with usual pharmacological care alone (very low certainty).

1 finding from 1 review