Findings

What do systematic reviews say?

1,192 questions · 1,243 findings · 151 reviews

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No studies found 252 · 20.3%GRADE not reported 180 · 14.5%Very low 291 · 23.4%Low 282 · 22.7%Moderate 174 · 14%High 64 · 5.1%

Dual mini-screw implant vs Single mini-screw implant

Acceptability · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

The review found no eligible studies for this question.

1 finding from 1 review

Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods 2014 · Cochrane All outcomes
Acceptability was not reported in any of the studies comparing two types of surgical anchorage
0 studies
No studies found

Dual mini-screw implant vs Single mini-screw implant

Adverse effects · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

The review found no eligible studies for this question.

1 finding from 1 review

Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods 2014 · Cochrane All outcomes
Adverse effects were not reported in any of the studies comparing two types of surgical anchorage
0 studies
No studies found

Beta2‐agonists vs placebo (single administration)

Maximal percentage fall in FEV1 · exercise‐induced asthma

1 finding from 1 review

Beta₂‐agonists for exercise‐induced asthma 2013 · Cochrane Headline outcomes only
no estimate extracted
72 studies · 799 participants
Moderate

Beta2‐agonists vs placebo (single administration)

Number of participants with an FEV1 fall > 10% · exercise‐induced asthma

Beta2‐agonists probably leads to lower number of participants with an FEV1 fall > 10% compared with placebo (single administration) (moderate certainty).

1 finding from 1 review

Beta₂‐agonists for exercise‐induced asthma 2013 · Cochrane Headline outcomes only
OR 0.08 [0.06, 0.13]
19 studies · 773 participants
Moderate

Beta2‐agonists vs placebo (single administration)

Maximal percentage fall in PEF · exercise‐induced asthma

1 finding from 1 review

Beta₂‐agonists for exercise‐induced asthma 2013 · Cochrane Headline outcomes only
no estimate extracted
14 studies · 92 participants
Low

Beta2‐agonists vs placebo (single administration)

Maximal percentage fall in FEF25‐75% · exercise‐induced asthma

1 finding from 1 review

Beta₂‐agonists for exercise‐induced asthma 2013 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 106 participants
Low

Beta2‐agonists vs placebo (single administration)

Side effects · exercise‐induced asthma

Beta2‐agonists showed no clear difference in side effects compared with placebo (single administration) (low certainty).

1 finding from 1 review

Beta₂‐agonists for exercise‐induced asthma 2013 · Cochrane Headline outcomes only
OR 0.83 [0.43, 1.59]
55 studies · 2165 participants
Low

Sodium hypochlorite 1.3% with MTAD final rinse vs Sodium hypochlorite 1.3% with normal saline final rinse

Adverse effects · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical…

The review found no eligible studies for this question.

1 finding from 1 review

Irrigants for non‐surgical root canal treatment in mature permanent teeth 2012 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Sodium hypochlorite 5.25% with EDTA 17% vs Sodium hypochlorite 1.3% with MTAD

Mean change in health-related quality of life or participant-expressed satisfaction with the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical…

The review found no eligible studies for this question.

1 finding from 1 review

Irrigants for non‐surgical root canal treatment in mature permanent teeth 2012 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Sodium hypochlorite 5.25% with EDTA 17% vs Sodium hypochlorite 1.3% with MTAD

Adverse effects · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical…

The review found no eligible studies for this question.

1 finding from 1 review

Irrigants for non‐surgical root canal treatment in mature permanent teeth 2012 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Low-gold (Midas) or silver-palladium (Albacast) alloy FDP vs High-gold content control alloy (JS C) FDP

Visual marginal discrepancy (3 years) · Patients receiving single crowns and FDPs; split-mouth

Low-gold (Midas) or silver-palladium (Albacast) alloy FDP showed no clear difference in visual marginal discrepancy (3 years) compared with high-gold content control alloy (JS C) FDP; GRADE not reported.

1 finding from 1 review

Interventions for replacing missing teeth: partially absent dentition 2012 · Cochrane All outcomes
3 years
RR 0.88 [0.06, 12.73]
1 study · 30 participants
GRADE not reported

Sodium hypochlorite (NaOCl), 2.5% to 5.25% vs Sodium hypochlorite 1%

Change in periapical radiolucency (radiography or CBCT), up to 1 year after treatment · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical…

The review found no eligible studies for this question.

1 finding from 1 review

Irrigants for non‐surgical root canal treatment in mature permanent teeth 2012 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Sodium hypochlorite 1.3% with MTAD final rinse vs Sodium hypochlorite 1.3% with normal saline final rinse

Proportion of participants with new or worsening signs/symptoms of inflammation requiring a revisit, up to 14 days after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical…

The review found no eligible studies for this question.

1 finding from 1 review

Irrigants for non‐surgical root canal treatment in mature permanent teeth 2012 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Cemented implant crown vs Screw-retained implant crown

Mechanical complications / prosthesis failure (4 years) · Patients with single-tooth implants receiving implant crowns; split-mouth

1 finding from 1 review

Interventions for replacing missing teeth: partially absent dentition 2012 · Cochrane All outcomes
4 years
No reports of any mechanical complications or failures with either type of prosthesis (narrative)
1 study · 12 participants
GRADE not reported

Sodium hypochlorite 5.25% vs Sodium hypochlorite 5.25% with hydrogen peroxide 3%

Adverse effects · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical…

The review found no eligible studies for this question.

1 finding from 1 review

Irrigants for non‐surgical root canal treatment in mature permanent teeth 2012 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Sodium hypochlorite (NaOCl), 2.5% to 5.25% vs Chlorhexidine, 0.2% to 2% (solution or gel)

Proportion of participants or samples with positive bacterial growth culture, up to 72 hours after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical…

Sodium hypochlorite (NaOCl), 2.5% to 5.25% showed no clear difference in proportion of participants or samples with positive bacterial growth… compared with chlorhexidine, 0.2% to 2% (solution or gel); GRADE not reported.

1 finding from 1 review

Irrigants for non‐surgical root canal treatment in mature permanent teeth 2012 · Cochrane All outcomes
RR 0.73 [0.34, 1.56]
2 studies · 62 participants
GRADE not reported

Sodium hypochlorite 5.25% with EDTA 17% vs Sodium hypochlorite 1.3% with MTAD

The review found no eligible studies for this question.

1 finding from 1 review

Irrigants for non‐surgical root canal treatment in mature permanent teeth 2012 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Sodium hypochlorite (NaOCl), 2.5% to 5.25% vs Sodium hypochlorite 1%

Proportion of participants with moderate to severe pain 72 hours to 14 days after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical…

The review found no eligible studies for this question.

1 finding from 1 review

Irrigants for non‐surgical root canal treatment in mature permanent teeth 2012 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Ceramic implant abutment vs Metal implant abutments (titanium)

Overall success rate · Patients receiving implant-supported single crowns / short-span FDPs

1 finding from 1 review

Interventions for replacing missing teeth: partially absent dentition 2012 · Cochrane All outcomes
Andersson 2003: 94% (16/17) ceramic vs 100% (12/12) titanium; Andersson 2001: 93% (28/30) ceramic vs 100% (35/35) titanium; no statistical analysis provided; no measurable / non-significant differences in alveolar bone…
2 studies · 107 participants
GRADE not reported

Sodium hypochlorite 5.25% with EDTA 17% vs Sodium hypochlorite 1.3% with MTAD

The review found no eligible studies for this question.

1 finding from 1 review

Irrigants for non‐surgical root canal treatment in mature permanent teeth 2012 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found