Cochrane · systematic review · CD003564
Beta₂‐agonists for exercise‐induced asthma
Bonini, M, Di Mambro, C, Calderon, MA, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 60%Moderate 2 · 40%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Beta2‐agonists compared with placebo (single administration) for exercise‐induced asthma
Population: exercise‐induced asthma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Maximal percentage fall in FEV1 Beta2‐agonists vs placebo (single administration) | no estimate extracted | 72 studies · 799 participants | Moderate Downgraded: imprecision, inconsistency |
Number of participants with an FEV1 fall > 10% Beta2‐agonists vs placebo (single administration) | OR 0.08 [0.06, 0.13] | 19 studies · 773 participants | Moderate Downgraded: imprecision, inconsistency |
Maximal percentage fall in PEF Beta2‐agonists vs placebo (single administration) | no estimate extracted | 14 studies · 92 participants | Low Downgraded: imprecision, inconsistency |
Maximal percentage fall in FEF25‐75% Beta2‐agonists vs placebo (single administration) | no estimate extracted | 8 studies · 106 participants | Low Downgraded: imprecision, inconsistency |
Side effects Beta2‐agonists vs placebo (single administration) | OR 0.83 [0.43, 1.59] | 55 studies · 2165 participants | Low Downgraded: imprecision, inconsistency |