What do systematic reviews say?

Intervention not reported

• Trypanocidal drugs for chronic asymptomatic Trypanosoma cruzi infection 2014 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 225 participants
  Low

Intervention not reported

It is very uncertain whether the intervention changes pulmonary haemorrhage (very low certainty).

• Corticosteroids for dengue infection 2014 · Cochrane Headline outcomes only
  RR 0.97 [0.06, 14.82]
  1 study · 63 participants
  Very low

Primary comparison for continuous passive motion (CPM) vs no CPM

It is very uncertain whether primary comparison for continuous passive motion (CPM) changes manipulation under anaesthesia Counts of manipulation under… compared with no CPM (very low certainty).

• Continuous passive motion following total knee arthroplasty in people with arthritis 2014 · Cochrane Headline outcomes only
  RR 0.34 [0.13, 0.89]
  8 studies · 581 participants
  Very low

CANNABIS REDUCTION: ANTIPSYCHOTIC 'A' vs ANTIPSYCHOTIC 'B' for

• Cannabis and schizophrenia 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 41 participants
  Moderate

Intervention not reported

• Immediate-release methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults 2014 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 207 participants
  High

Intensive insulin therapy vs conventional insulin therapy

Intensive insulin therapy may leads to lower occurrence of CIP/CIM ‐ in total population randomised compared with conventional insulin therapy (low certainty).

• Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
  RR 0.7 [0.6, 0.82]
  2 studies · 2748 participants
  Low

Corticosteroids vs placebo compared

Corticosteroids showed no clear difference in death ‐ death at 180 days in total population randomised compared with placebo compared (high certainty).

• Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
  RR 0.99 [0.64, 1.52]
  1 study · 180 participants
  High

Early physical therapy vs control

Early physical therapy showed no clear difference in occurrence of CIP/CIM ‐ in the total population randomised compared with control (low certainty).

• Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
  RR 0.81 [0.6, 1.08]
  1 study · 104 participants
  Low

Early physical therapy vs control

Early physical therapy probably leads to lower occurrence of CIP/CIM ‐ in screened population compared with control (moderate certainty).

• Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
  RR 0.62 [0.39, 0.96]
  1 study · 82 participants
  Moderate

Early physical therapy vs control

Early physical therapy showed no clear difference in serious adverse events ‐ in total population randomised compared with control (moderate certainty).

• Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
  RR 3.36 [0.14, 80.62]
  1 study · 104 participants
  Moderate

Electrical muscle stimulation vs control

It is very uncertain whether electrical muscle stimulation changes occurrence of CIP/CIM ‐ in the total population randomised compared with control (very low certainty).

• Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
  RR 0.94 [0.78, 1.15]
  1 study · 140 participants
  Very low

Electrical muscle stimulation vs control

It is very uncertain whether electrical muscle stimulation changes occurrence of CIP/CIM ‐ in screened population compared with control (very low certainty).

• Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
  RR 0.32 [0.1, 1.01]
  1 study · 52 participants
  Very low

Intensive insulin therapy vs conventional insulin therapy

Intensive insulin therapy probably leads to lower occurrence of CIP/CIM ‐ in screened population compared with conventional insulin therapy (moderate certainty).

• Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
  RR 0.65 [0.55, 0.77]
  2 studies · 825 participants
  Moderate

Intensive insulin therapy vs conventional insulin therapy

• Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 2748 participants
  High

Intensive insulin therapy vs conventional insulin therapy

• Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 2748 participants
  High

Intensive insulin therapy vs conventional insulin therapy

Intensive insulin therapy showed no clear difference in death ‐ at 30 days after ICU admission, in total population randomised compared with conventional insulin therapy (high certainty).

• Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
  RR 0.94 [0.8, 1.1]
  2 studies · 2748 participants
  High

Intensive insulin therapy vs conventional insulin therapy

Intensive insulin therapy showed no clear difference in death ‐ at 180 days after ICU admission, in total population… compared with conventional insulin therapy (moderate certainty).

• Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
  RR 0.87 [0.76, 1]
  2 studies · 2748 participants
  Moderate

Intensive insulin therapy vs conventional insulin therapy

Intensive insulin therapy leads to higher serious adverse events, ‐ in total population randomised ‐… compared with conventional insulin therapy (high certainty).

• Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
  RR 6.27 [4.15, 9.49]
  2 studies · 2748 participants
  High

Corticosteroids vs placebo compared

Corticosteroids showed no clear difference in occurrence of CIP/CIM ‐ in total population randomised compared with placebo compared (low certainty).

• Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
  RR 1.27 [0.77, 2.08]
  1 study · 180 participants
  Low

Corticosteroids vs placebo compared

Corticosteroids showed no clear difference in occurrence of CIP/CIM ‐ in screened population compared with placebo compared (moderate certainty).

• Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
  RR 1.09 [0.53, 2.26]
  1 study · 92 participants
  Moderate