2nd degree tear · women in the second stage of labour without epidural anaesthesia
Any upright showed no clear difference in trauma to the birth canal that required suturing: second degree… compared with supine position (low certainty).
1 finding from 1 review
Trauma to the birth canal that required suturing: third/fourth degree tears · women in the second stage of labour without epidural anaesthesia
It is very uncertain whether any upright changes trauma to the birth canal that required suturing: third/fourth… compared with supine position (very low certainty).
1 finding from 1 review
Blood loss > 500 mL · women in the second stage of labour without epidural anaesthesia
Any upright probably leads to higher blood loss > 500 mL compared with supine position (moderate certainty).
1 finding from 1 review
Admission to neonatal intensive care unit · women in the second stage of labour without epidural anaesthesia
Any upright showed no clear difference in admission to neonatal intensive care unit compared with supine position (low certainty).
1 finding from 1 review
Closure of macular hole · people with symptomatic vitreomacular adhesion
Ocriplasmin injection leads to higher closure of macular hole compared with control (high certainty).
1 finding from 1 review
RR 2.87 [1.5, 5.51]
Studies not reported
High
Complete posterior vitreous detachment · people with symptomatic vitreomacular adhesion
Ocriplasmin injection leads to higher complete posterior vitreous detachment compared with control (high certainty).
1 finding from 1 review
RR 2.94 [1.39, 6.24]
Studies not reported
High
3‐line or greater improvement in best‐corrected visual acuity · people with symptomatic vitreomacular adhesion
Ocriplasmin injection probably leads to higher 3‐line or greater improvement in best‐corrected visual acuity compared with control (moderate certainty).
1 finding from 1 review
RR 1.95 [1.07, 3.53]
Studies not reported
Moderate
Requirement for vitrectomy · people with symptomatic vitreomacular adhesion
Ocriplasmin injection probably leads to lower requirement for vitrectomy compared with control (moderate certainty).
1 finding from 1 review
RR 0.67 [0.5, 0.91]
Studies not reported
Moderate
Mean change in validated visual function questionnaire score from baseline Score ranges from 0 to 100, higher scores are better visual function · people with symptomatic vitreomacular adhesion
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Adverse events (ocular problems) · people with symptomatic vitreomacular adhesion
Ocriplasmin injection probably leads to higher any ocular adverse event compared with control (moderate certainty).
1 finding from 1 review
RR 1.22 [1.09, 1.37]
Studies not reported
Moderate
Postextubation stridor (defined as any inspiratory sound or persistent barking, or presence of sternal or intercostal retractions postextubation) · Children up to eight years undergoing general anaesthesia
It is very uncertain whether cuffed changes postextubation stridor (defined as any inspiratory sound or… compared with uncuffed tubes (very low certainty).
1 finding from 1 review
Need for ETT exchange (defined as more than one attempt to arrive at the final endotracheal tube size) · Children up to eight years undergoing general anaesthesia
It is very uncertain whether cuffed changes need for ETT exchange (defined as more than one attempt to arrive at… compared with uncuffed tubes (very low certainty).
1 finding from 1 review
Need for tracheal re‐intubation for postoperative stridor (defined as the need to re‐intubate to assure oxygenation to deal with postextubation stridor) · Children up to eight years undergoing general anaesthesia
It is very uncertain whether cuffed changes need for tracheal re‐intubation for postoperative stridor (defined… compared with uncuffed tubes (very low certainty).
1 finding from 1 review
Need for epinephrine to treat stridor (defined as the need to use epinephrine to treat postextubation stridor) · Children up to eight years undergoing general anaesthesia
It is very uncertain whether cuffed changes need for epinephrine to treat stridor (defined as the need to use… compared with uncuffed tubes (very low certainty).
1 finding from 1 review
Need for intensive care unit (ICU) admission to treat post extubation stridor (as defined by the trial authors) · Children up to eight years undergoing general anaesthesia
It is very uncertain whether cuffed changes need for intensive care unit (ICU) admission to treat post… compared with uncuffed tubes (very low certainty).
1 finding from 1 review
Cost of medical gas (described in the study by the hospital expenses for medical gases per participant in Euros) · Children up to eight years undergoing general anaesthesia
1 finding from 1 review
Need for corticosteroid to treat stridor (defined as the need to use corticosteroid to treat postextubation stridor) · Children up to eight years undergoing general anaesthesia
It is very uncertain whether cuffed changes need for corticosteroid to treat stridor (defined as the need to use… compared with uncuffed tubes (very low certainty).
1 finding from 1 review
All‐cause mortality · Patients with hip fracture repair
It is very uncertain whether neuraxial block changes mortality compared with general anaesthesia (very low certainty).
1 finding from 1 review
Pneumonia · Patients with hip fracture repair
It is very uncertain whether neuraxial block changes pneumonia compared with general anaesthesia (very low certainty).
1 finding from 1 review
Myocardial infarction · Patients with hip fracture repair
It is very uncertain whether neuraxial block changes myocardial infarction compared with general anaesthesia (very low certainty).
1 finding from 1 review