Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,749 questions · 17,858 findings · 1,266 reviews

No studies found 4,359 · 24.4%GRADE not reported 2,348 · 13.1%Very low 4,634 · 25.9%Low 4,000 · 22.4%Moderate 2,052 · 11.5%High 465 · 2.6%

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Summary of findings table ‐ Indicated prevention interventions vs control group

QoL · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Indicated prevention interventions vs control group

Adverse events at study endpoint · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Indicated prevention interventions vs control group

Psychological functioning and impairment at study endpoint (higher score = higher disability) · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Indicated prevention interventions vs control group

Depressive symptoms · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Indicated prevention interventions vs control group

Anxiety · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Indicated prevention interventions vs control group

Distress/PTSD symptoms at study endpoint (higher score = higher severity) · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Selective prevention interventions vs control group

Diagnosis of mental disorders at study endpoint · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Selective prevention interventions vs control group

QoL · preventing mental disorders
2 findings from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Taking adherence · solid organ transplant recipients

Interventions for increasing immunosuppressant medication adherence showed no clear difference in taking adherence compared with standard care (low certainty).

1 finding from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Dosing adherence · solid organ transplant recipients

Interventions for increasing immunosuppressant medication adherence may leads to higher dosing adherence compared with standard care (low certainty).

1 finding from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Timing adherence · solid organ transplant recipients

Interventions for increasing immunosuppressant medication adherence showed no clear difference in timing adherence compared with standard care (low certainty).

1 finding from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Drug holidays · solid organ transplant recipients

Interventions for increasing immunosuppressant medication adherence showed no clear difference in drug holidays compared with standard care (low certainty).

1 finding from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Adherence · solid organ transplant recipients

It is very uncertain whether interventions for increasing immunosuppressant medication adherence changes self‐reported adherence (proportion) compared with standard care (very low certainty).

2 findings from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Proportion of immunosuppressant trough concentration levels at target · solid organ transplant recipients

It is very uncertain whether interventions for increasing immunosuppressant medication adherence changes proportion of immunosuppressant trough concentration levels at target compared with standard care (very low certainty).

1 finding from 1 review

Interventions (ibuprofen, tolfenamic acid, aspirin, tranexamic acid) vs placebo or active comparators (paracetamol, tranexamic acid)

Menstrual blood loss: mean loss

Interventions (ibuprofen, tolfenamic acid, aspirin, tranexamic acid) showed no clear difference in menstrual blood loss (alkaline hematin method) compared with placebo or active comparators (paracetamol, tranexamic acid); GRADE not reported.

2 findings from 1 review

Interventions (ibuprofen, tolfenamic acid, aspirin, tranexamic acid) vs placebo or active comparators (paracetamol, tranexamic acid)

Duration of bleeding (menstrual diary)

Interventions (ibuprofen, tolfenamic acid, aspirin, tranexamic acid) showed no clear difference in duration of bleeding (menstrual diary) compared with placebo or active comparators (paracetamol, tranexamic acid); GRADE not reported.

1 finding from 1 review