Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,017 questions · 1,061 findings · 131 reviews

No studies found 193 · 18.2%GRADE not reported 65 · 6.1%Very low 237 · 22.3%Low 325 · 30.6%Moderate 187 · 17.6%High 54 · 5.1%

Primary analysis: less vs more frequent

Catheter colonization any positive semiquantitative or quantitative culture from the distal catheter segment · patients with intravenous administration set replacement

Primary analysis: less showed no clear difference in catheter colonization any positive semiquantitative or quantitative… compared with more frequent (moderate certainty).

1 finding from 1 review

Primary analysis: less vs more frequent

All‐cause BSI any positive blood culture drawn from a peripheral vein taken whilst the IVD is in situ, or within 48 hours of removal (O'Grady 2002) · patients with intravenous administration set replacement

Primary analysis: less showed no clear difference in all‐cause BSI any positive blood culture drawn from a peripheral… compared with more frequent (low certainty).

1 finding from 1 review

Postoperative feeding via nasojejunal tube vs no postoperative parental nutrition (conventional intravenous electrolyte solution)

Infections (overall) · adult patients after liver transplantation.

It is very uncertain whether postoperative feeding via nasojejunal tube changes infections (overall) compared with no postoperative parental nutrition (conventional intravenous… (very low certainty).

1 finding from 1 review

Postoperative feeding via nasojejunal tube vs no postoperative parental nutrition (conventional intravenous electrolyte solution)

Bacterial infection · adult patients after liver transplantation.

It is very uncertain whether postoperative feeding via nasojejunal tube changes infections (bacterial) compared with no postoperative parental nutrition (conventional intravenous… (very low certainty).

1 finding from 1 review

Postoperative feeding via nasojejunal tube vs no postoperative parental nutrition (conventional intravenous electrolyte solution)

Infections (viral) · adult patients after liver transplantation.

It is very uncertain whether postoperative feeding via nasojejunal tube changes infections (viral) compared with no postoperative parental nutrition (conventional intravenous… (very low certainty).

1 finding from 1 review

Parenteral nutrition plus branched‐chain‐amino‐acid‐enriched formula vs standard isotonic intravenous glucose solution

Mortality [within first 10 weeks after liver transplantation] · adult patients after liver transplantation.

Parenteral nutrition plus branched‐chain‐amino‐acid‐enriched formula showed no clear difference in mortality [within first 10 weeks after liver transplantation] compared with standard isotonic intravenous glucose solution (low certainty).

1 finding from 1 review

Standard parenteral nutrition vs standard isotonic intravenous glucose solution

Length of hospital stay after liver transplantation [days] · adult patients after liver transplantation.
2 findings from 1 review

Standard parenteral nutrition vs standard isotonic intravenous glucose solution

Mortality [within first 10 weeks after liver transplantation] · adult patients after liver transplantation.

Standard parenteral nutrition may leads to lower mortality [within first 10 weeks after liver transplantation] compared with standard isotonic intravenous glucose solution (low certainty).

1 finding from 1 review

Oral paracetamol vs placebo

At least 50% reduction in pain · Patients requiring surgical removal of a lower wisdom tooth or teeth, with baseline moderate to severe pain (surgery under local…

Paracetamol (single oral dose, any dose or formulation; subgroups up… led to higher achieving at least 50% pain relief at 4 hours (using pain intensity… compared with placebo; GRADE not reported.

3 findings from 1 review

Oral paracetamol vs placebo

Patients with one or more adverse events · Patients requiring surgical removal of a lower wisdom tooth or teeth, with baseline moderate to severe pain (surgery under local…

Paracetamol (single oral dose, any dose or formulation; subgroups up… showed no clear difference in patients with one or more adverse events compared with placebo; GRADE not reported.

1 finding from 1 review

Oral paracetamol vs placebo

Participant‐reported pain relief of 50% or greater · Patients requiring surgical removal of a lower wisdom tooth or teeth, with baseline moderate to severe pain (surgery under local…

Paracetamol (single oral dose, any dose or formulation; subgroups up… led to higher achieving at least 50% pain relief at 6 hours (using pain relief… compared with placebo; GRADE not reported.

1 finding from 1 review