Findings

What do systematic reviews say?

1,126 questions · 1,225 findings · 111 reviews

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No studies found 235 · 19.2%GRADE not reported 260 · 21.2%Very low 207 · 16.9%Low 271 · 22.1%Moderate 177 · 14.4%High 75 · 6.1%

Vitamin A vs placebo

Change in vitamin A concentrations (µmol/L) · adults with HIV infection

1 finding from 1 review

Micronutrient supplementation in adults with HIV infection 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 495 participants
Low

Vitamin D vs placebo

Change in 25(OH) vitamin D concentrations (ng/mL) · adults with HIV infection

1 finding from 1 review

Micronutrient supplementation in adults with HIV infection 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 299 participants
Moderate

Summary of findings table ‐ Vitamin B12 supplementation vs no supplementation or placebo

Maternal vitamin B12 deficiency · pregnant women

It is very uncertain whether summary of findings table ‐ Vitamin B12 supplementation changes maternal vitamin B12 deficiency compared with placebo/no vitamin B12 supplementation (very low certainty).

1 finding from 1 review

Vitamin B12 supplementation during pregnancy for maternal and child health outcomes 2024 · Cochrane Headline outcomes only
RR 0.38 [0.28, 0.51]
2 studies · 272 participants
Very low

Vitamin D vs placebo or no intervention

Cancer occurrence · healthy participants or recruited among the general population; individuals diagnosed with a specific disease in a stable phase or with…

Vitamin D showed no clear difference in cancer occurrence compared with placebo or no intervention (moderate certainty).

1 finding from 1 review

Vitamin D supplementation for prevention of cancer in adults 2014 · Cochrane Headline outcomes only
RR 1 [0.94, 1.06]
18 studies · 50623 participants
Moderate

Vitamin D vs placebo or no intervention

All‐cause mortality · healthy participants or recruited among the general population; individuals diagnosed with a specific disease in a stable phase or with…

Vitamin D may leads to lower all‐cause mortality compared with placebo or no intervention (low certainty).

1 finding from 1 review

Vitamin D supplementation for prevention of cancer in adults 2014 · Cochrane Headline outcomes only
RR 0.93 [0.88, 0.98]
15 studies · 49866 participants
Low

Vitamin D vs placebo or no intervention

Health‐related quality of life · healthy participants or recruited among the general population; individuals diagnosed with a specific disease in a stable phase or with…

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin D supplementation for prevention of cancer in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamin D vs placebo or no intervention

Health economics · healthy participants or recruited among the general population; individuals diagnosed with a specific disease in a stable phase or with…

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin D supplementation for prevention of cancer in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamin C vs placebo

Health‐related quality of life (HRQL) · people with asthma

1 finding from 1 review

Vitamin C for asthma and exercise‐induced bronchoconstriction 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 201 participants
Low

Vitamin C vs placebo

Adverse events · adults and children with exercise‐induced bronchoconstriction/asthma

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin C for asthma and exercise‐induced bronchoconstriction 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamin C vs placebo

Asthma exacerbations · people with asthma

1 finding from 1 review

Vitamin C for asthma and exercise‐induced bronchoconstriction 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low

Vitamin C vs placebo

Lung function: FEV1 mL (change from baseline) · people with asthma

1 finding from 1 review

Vitamin C for asthma and exercise‐induced bronchoconstriction 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 201 participants
Moderate

Vitamin C vs placebo

Asthma symptoms · people with asthma

1 finding from 1 review

Vitamin C for asthma and exercise‐induced bronchoconstriction 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 201 participants
Moderate

Vitamin C vs placebo

Adverse events · people with asthma

1 finding from 1 review

Vitamin C for asthma and exercise‐induced bronchoconstriction 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 41 participants
Very low

Vitamin C vs placebo

Health‐related quality of life (HRQL) · adults and children with exercise‐induced bronchoconstriction/asthma

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin C for asthma and exercise‐induced bronchoconstriction 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamin C vs placebo

Asthma exacerbations · adults and children with exercise‐induced bronchoconstriction/asthma

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin C for asthma and exercise‐induced bronchoconstriction 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamin C vs placebo

Lung function: FEV1 % drop Postexercise · adults and children with exercise‐induced bronchoconstriction/asthma

1 finding from 1 review

Vitamin C for asthma and exercise‐induced bronchoconstriction 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 8 participants
Low

Vitamin C vs placebo

Asthma symptoms · adults and children with exercise‐induced bronchoconstriction/asthma

1 finding from 1 review

Vitamin C for asthma and exercise‐induced bronchoconstriction 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 8 participants
Low

hAMMSC‐CM + vitamin C vs hAMMSC‐CM

Primary outcome: prevention of ulcer · ulceration caused by nerve damage in leprosy

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

hAMMSC‐CM + vitamin C vs hAMMSC‐CM

Ulcer healing · ulceration caused by nerve damage in leprosy

2 findings from 1 review

Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 44 participants
Very low
Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 44 participants
Very low

hAMMSC‐CM + vitamin C vs hAMMSC‐CM

Adverse events associated with treatment · ulceration caused by nerve damage in leprosy

1 finding from 1 review

Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 44 participants
Very low