Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

91 questions · 96 findings · 9 reviews · Heart

No studies found 18 · 18.8%GRADE not reported 10 · 10.4%Very low 20 · 20.8%Low 21 · 21.9%Moderate 25 · 26%High 2 · 2.1%

Summary of findings ‐ structured telephone support or telemonitoring vs usual care

All‐cause mortality: Structured telephone support versus usual care · patients with heart failure

Summary of findings ‐ structured telephone support or telemonitoring probably leads to lower all‐cause mortality: Structured telephone support versus usual care compared with usual care ‐ all‐cause mortality (moderate certainty).

1 finding from 1 review

Summary of findings ‐ structured telephone support or telemonitoring vs usual care

Death (all causes) · patients with heart failure

Summary of findings ‐ structured telephone support or telemonitoring probably leads to lower all‐cause mortality: Telemonitoring versus usual care compared with usual care ‐ all‐cause mortality (moderate certainty).

1 finding from 1 review

Summary of findings ‐ structured telephone support or telemonitoring vs usual care ‐ all‐cause hospitalisation

Hospitalisation (any cause) · patients with heart failure

It is very uncertain whether summary of findings ‐ structured telephone support or telemonitoring changes all‐cause hospitalisation: Structured telephone support verus usual… compared with usual care ‐ all‐cause hospitalisation (very low certainty).

2 findings from 1 review

Summary of findings ‐ structured telephone support or telemonitoring vs usual care

Heart failure hospitalisation (RR) · patients with heart failure

Summary of findings ‐ structured telephone support or telemonitoring probably leads to lower CHF‐related hospitalisation: Structured telephone support versus… compared with usual care ‐ heart failure‐related hospitalisation (moderate certainty).

2 findings from 1 review

Summary of findings for the main comparison. Implantable loop recorder vs conventional diagnostic workup

All‐cause long‐term mortality · people with unexplained recurrent syncope

It is very uncertain whether summary of findings for the main comparison. Implantable loop recorder changes all‐cause long‐term mortality compared with conventional diagnostic workup (very low certainty).

1 finding from 1 review

Summary of findings for the main comparison. Implantable loop recorder vs conventional diagnostic workup

Aetiologic diagnosis · people with unexplained recurrent syncope

Summary of findings for the main comparison. Implantable loop recorder probably leads to lower aetiologic diagnosis compared with conventional diagnostic workup (moderate certainty).

1 finding from 1 review

Summary of findings table for the comparison of 'intensified patient care' vs usual care

Adherence to antipsychotic medication: number of missed doses, average endpoint data, short term (up to 6 months) · People receiving lipid‐lowering medications

Summary of findings table for the comparison of 'intensified patient… probably leads to higher medication adherence at ≤ 6 months compared with 'usual care' (moderate certainty).

1 finding from 1 review

Summary of findings table for the comparison of 'intensified patient care' vs usual care

Medication adherence (dichotomous) · People receiving lipid‐lowering medications

Summary of findings table for the comparison of 'intensified patient… leads to higher medication adherence at > 6 months compared with 'usual care' (high certainty).

1 finding from 1 review

Summary of findings table ‐ Continuous infusion of intravenous loop diuretics vs bolus injection of intravenous loop diuretics

Mortality before hospital discharge · adults (aged greater than 18 years) with acute heart failure

Summary of findings table ‐ Continuous infusion of intravenous loop… showed no clear difference in all‐cause mortality (from admission to discharge) compared with bolus injection of intravenous loop diuretics (low certainty).

1 finding from 1 review