Suspected ototoxicity · people (of any age) with CSOM
1 finding from 1 review
Resolution of ear discharge at short‐term
Antibiotic eardrops (with or without a corticosteroid) probably leads to higher resolution of ear discharge at short‐term compared with oral antibiotics (moderate certainty).
1 finding from 1 review
Adverse events
Antibiotic eardrops (with or without a corticosteroid) showed no clear difference in adverse events compared with oral antibiotics (low certainty).
1 finding from 1 review
Serious complications
1 finding from 1 review
Resolution of ear discharge at intermediate‐term
Antibiotic eardrops (with or without a corticosteroid) probably leads to higher resolution of ear discharge at intermediate‐term compared with oral antibiotics (moderate certainty).
1 finding from 1 review
Duration of ear discharge
1 finding from 1 review
Tube blockage
Antibiotic eardrops (with or without a corticosteroid) showed no clear difference in tube blockage compared with oral antibiotics (low certainty).
1 finding from 1 review
Health‐related quality of life
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Generic ‐ CHQ
1 finding from 1 review
Disease‐specific quality of life
1 finding from 1 review
Disease‐specific quality of life · children aged 6 months to 12 years with otitis media with effusion (OME)
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Presence/persistence of OME · children aged 6 months to 12 years with otitis media with effusion (OME)
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Adverse event: systemic corticosteroid side effects · children aged 6 months to 12 years with otitis media with effusion (OME)
It is very uncertain whether topical (intranasal) steroids changes adverse event: systemic corticosteroid side effects compared with placebo (very low certainty).
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Hearing · children aged 6 months to 12 years with otitis media with effusion (OME)
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Disease‐specific quality of life · children aged 6 months to 12 years with otitis media with effusion (OME)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Presence/persistence of OME · children aged 6 months to 12 years with otitis media with effusion (OME)
It is very uncertain whether topical (intranasal) steroids changes presence/persistence of OME (short‐term); assumed ICC = 0.5 compared with no treatment (very low certainty).
1 finding from 1 review
RR 0.72 [0.57, 0.91]
Studies not reported
Very low
Adverse event: systemic corticosteroid side effects · children aged 6 months to 12 years with otitis media with effusion (OME)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Hearing · children aged 6 months to 12 years with otitis media with effusion (OME)
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Intervention not reported
Pain: severity score day 1 Scale from: 1 to 5 · patients with tonsillectomy
1 finding from 1 review
Median days with hearing loss [3 months] · Children with otitis media with effusion
1 finding from 1 review
no estimate extracted
200 participants
Moderate