Disease-free survival · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
1 finding from 1 review
Oral mucositis (moderate to severe) · Adults with solid cancers receiving fluorouracil (5FU) and leucovorin
It is very uncertain whether oral cryotherapy for 30 minutes changes oral mucositis (moderate to severe) compared with oral cryotherapy for 60 minutes (very low certainty).
1 finding from 1 review
Oral mucositis (severe) · Adults with solid cancers receiving fluorouracil (5FU) and leucovorin
It is very uncertain whether oral cryotherapy for 30 minutes changes oral mucositis (severe) compared with oral cryotherapy for 60 minutes (very low certainty).
1 finding from 1 review
Oral mucositis (any severity) · Adults with solid cancers receiving fluorouracil (5FU) and leucovorin
It is very uncertain whether oral cryotherapy for 30 minutes changes oral mucositis (any severity) compared with oral cryotherapy for 60 minutes (very low certainty).
1 finding from 1 review
Chemotherapy vs Placebo
Outcome not reported · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
The review found no eligible studies for this question.
1 finding from 1 review
Altered fractionation radiotherapy vs Chemoradiotherapy (concurrent, standard fractionation)
Outcome not reported · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
The review found no eligible studies for this question.
1 finding from 1 review
Total mortality · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
Accelerated/split-course radiotherapy showed no clear difference in total mortality compared with conventional (standard) fractionation radiotherapy; GRADE not reported.
1 finding from 1 review
Dental caries prevalence and severity · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in dental caries/severity between ART regimens (very low certainty).
1 finding from 1 review
Angular cheilitis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No eligible studies compared angular cheilitis between different ART regimens.
1 finding from 1 review
Recurrent oral ulceration prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in recurrent oral ulceration between ART regimens (very low certainty).
1 finding from 1 review
Dental development and maturation · Children and adolescents (<18 years) living with HIV (CLWH)
No eligible studies compared dental development and maturation between different ART regimens.
1 finding from 1 review
Acute necrotising ulcerative periodontitis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in acute necrotising ulcerative periodontitis between ART regimens (very low certainty).
1 finding from 1 review
Kaposi's sarcoma prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in kaposi's sarcoma between ART regimens (very low certainty).
1 finding from 1 review
Linear gingival erythema prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in linear gingival erythema between ART regimens (very low certainty).
1 finding from 1 review
Chronic herpes simplex infection prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in chronic herpes simplex infection between ART regimens (very low certainty).
1 finding from 1 review
Oral hairy leukoplakia prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No eligible studies compared oral hairy leukoplakia between different ART regimens.
1 finding from 1 review
Gingivitis · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in gingivitis between ART regimens (very low certainty).
1 finding from 1 review
Oral candidiasis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
cART was associated with a significantly lower prevalence of oral candidiasis than monotherapy or dual therapy (very low certainty).
1 finding from 1 review
OR 0.22 [0.16, 0.29]
4 studies
Very low
Persistent parotid enlargement prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in persistent parotid enlargement between ART regimens (very low certainty).
1 finding from 1 review
Locoregional control · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
Low dose rate interstitial radiotherapy showed no clear difference in locoregional control compared with high dose rate interstitial radiotherapy; GRADE not reported.
1 finding from 1 review