Cryotherapy (ice chips) 30 minutes vs Cryotherapy (ice chips) 60 minutes: Oral mucositis (moderate to severe)
- Population
- Adults with solid cancers receiving fluorouracil (5FU) and leucovorin
- Intervention
- Cryotherapy (ice chips) 30 minutes
- Comparison
- Cryotherapy (ice chips) 60 minutes
- Outcome
- Oral mucositis (moderate to severe)
It is very uncertain whether oral cryotherapy for 30 minutes changes oral mucositis (moderate to severe) compared with oral cryotherapy for 60 minutes (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Oral cryotherapy for 30 minutes vs Oral cryotherapy for 60 minutes Oral mucositis (moderate to severe) · Adults with solid cancers receiving fluorouracil (5FU) and leucovorin It is very uncertain whether oral cryotherapy for 30 minutes changes oral mucositis (moderate to severe) compared with oral cryotherapy for 60 minutes (very low certainty). Interventions for preventing oral mucositis in patients with cancer receiving treatment: oral cryotherapy (2015) · Cochrane All outcomes | RR 0.68 [0.36, 1.30] | 1 study · 178 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for preventing oral mucositis in patients with cancer receiving treatment: oral cryotherapy 2015 · Cochrane All outcomes | 2015-06 | Not listed | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Cryotherapy (ice chips) 30 minutes vs Cryotherapy (ice chips) 60 minutes · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.