Length of hospital stay · patients with preterm infants
1 finding from 1 review
Breastfeeding (exclusive at discharge) · patients with preterm infants
Transfer from incubator to cot at lower showed no clear difference in proportion of infants exclusive breastfeeding at discharge compared with higher body weight (high certainty).
1 finding from 1 review
Proportion of participants requiring further IOP‐lowering interventions (additional surgery, medications, or both) (lower number of events is better) · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure
It is very uncertain whether phacoemulsification changes proportion of participants requiring further IOP‐lowering… compared with laser peripheral iridotomy (very low certainty).
1 finding from 1 review
Proportion of participants with 1 or more recurrent APAC episodes in the same eye (lower number of events is better) · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure
It is very uncertain whether phacoemulsification changes proportion of participants with 1 or more recurrent APAC episodes in… compared with laser peripheral iridotomy (very low certainty).
1 finding from 1 review
Mean number of antiglaucoma medications at 1‐year · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure
1 finding from 1 review
Mean IOP ( · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure
1 finding from 1 review
Total mortality · adult patients with hypertension
Lower BP target showed no clear difference in total mortality compared with standard BP target (high certainty).
1 finding from 1 review
RR 0.95 [0.86, 1.05]
Studies not reported
High
Total serious adverse events№ of participants: 18165(6 RCTs) · adult patients with hypertension
Lower BP target showed no clear difference in total serious adverse events№ of participants: 18165(6 RCTs) compared with standard BP target (moderate certainty).
1 finding from 1 review
RR 1.04 [0.99, 1.08]
Studies not reported
Moderate
Myocardial infarction · adult patients with hypertension
Lower BP target may leads to lower myocardial infarction№ of participants: 38,198(8 RCTs) compared with standard BP target (low certainty).
1 finding from 1 review
RR 0.84 [0.73, 0.96]
Studies not reported
Low
Stroke · adult patients with hypertension
Lower BP target showed no clear difference in stroke№ of participants: 37,087(7 RCTs) compared with standard BP target (low certainty).
1 finding from 1 review
RR 0.88 [0.77, 1.01]
Studies not reported
Low
Congestive heart failure · adult patients with hypertension
Lower BP target may leads to lower congestive heart failure№ of participants: 15,859(5 RCTs) compared with standard BP target (low certainty).
1 finding from 1 review
RR 0.75 [0.6, 0.92]
Studies not reported
Low
Other serious adverse events · adult patients with hypertension
Lower BP target may leads to higher other serious adverse events compared with standard BP target (low certainty).
1 finding from 1 review
RR 1.44 [1.32, 1.59]
Studies not reported
Low
Myocardial infarction · people with or without existing cardiovascular disease, men and women
Homocysteine‐lowering interventions (Vitamin B6 (pyridoxine;… showed no clear difference in myocardial infarction compared with placebo or standard care (high certainty).
1 finding from 1 review
Stroke · people with or without existing cardiovascular disease, men and women
Homocysteine‐lowering interventions (Vitamin B6 (pyridoxine;… leads to lower stroke compared with placebo or standard care (high certainty).
1 finding from 1 review
Death by any cause · people with or without existing cardiovascular disease, men and women
Homocysteine‐lowering interventions (Vitamin B6 (pyridoxine;… showed no clear difference in death by any cause compared with placebo or standard care (high certainty).
1 finding from 1 review
Adverse events · people with or without existing cardiovascular disease, men and women
Homocysteine‐lowering interventions (Vitamin B6 (pyridoxine;… showed no clear difference in adverse events compared with placebo or standard care (high certainty).
1 finding from 1 review
Systolic blood pressure · people with CKD
1 finding from 1 review
Diastolic blood pressure · people with CKD
1 finding from 1 review
Albuminuria · people with CKD
1 finding from 1 review
Extracellular fluid volume · people with CKD
1 finding from 1 review