Cochrane · systematic review · CD010070
Altered dietary salt intake for people with chronic kidney disease
McMahon, EJ, Campbell, KL, Bauer, JD, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
Kidney and TransplantAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 28.6%Low 1 · 14.3%Moderate 1 · 14.3%High 3 · 42.9%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Lower salt intake versus higher salt intake for participants with chronic kidney disease
Population: participants with CKD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Systolic blood pressure Lower salt intake vs higher salt intake | no estimate extracted | 19 studies · 1261 participants | High |
Diastolic blood pressure Lower salt intake vs higher salt intake | no estimate extracted | 19 studies · 1257 participants | High |
Albuminuria Lower salt intake vs higher salt intake | no estimate extracted | 6 studies · 501 participants | High |
Extracellular fluid volume Lower salt intake vs higher salt intake | no estimate extracted | 3 studies · 187 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Weight Lower salt intake vs higher salt intake | no estimate extracted | 12 studies · 759 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Reduction in antihypertensive dose Lower salt intake vs higher salt intake | RR 2.45 [0.98, 6.08] | 7 studies · 664 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Symptomatic hypotension Lower salt intake vs higher salt intake | RR 6.7 [2.4, 18.69] | 6 studies · 478 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |