Pain ‐ Pain at 3 to 7 days · children with acute otitis media
Immediate antibiotics showed no clear difference in pain ‐ Pain at 3 to 7 days compared with expectant observation (moderate certainty).
1 finding from 1 review
Mean postoperative best‐corrected visual acuity · people with cataract and age‐related macular degeneration
1 finding from 1 review
Mean change in cumulated drusen or geographic atrophy area size (CDGAS) · people with cataract and age‐related macular degeneration
1 finding from 1 review
no estimate extracted
6 participants
GRADE not reported
Development of choroidal neovascularization · people with cataract and age‐related macular degeneration
It is very uncertain whether immediate cataract surgery changes development of choroidal neovascularization compared with delayed cataract surgery (very low certainty).
1 finding from 1 review
Vision‐related quality of life · people with cataract and age‐related macular degeneration
1 finding from 1 review
Complications · people with cataract and age‐related macular degeneration
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Death · HIV‐positive, treatment‐naive children aged one to 12 years old
It is very uncertain whether IMMEDIATE initiation of cART changes death compared with DEFERRED initiation of cART (very low certainty).
1 finding from 1 review
CDC Category C disease (number of children) · HIV‐positive, treatment‐naive children aged one to 12 years old
It is very uncertain whether IMMEDIATE initiation of cART changes CDC Category C disease (number of children) compared with DEFERRED initiation of cART (very low certainty).
1 finding from 1 review
CDC Category B disease (numbers of children) Peto Odds Ratio · HIV‐positive, treatment‐naive children aged one to 12 years old
It is very uncertain whether IMMEDIATE initiation of cART changes CDC Category B disease (numbers of children) Peto Odds Ratio compared with DEFERRED initiation of cART (very low certainty).
1 finding from 1 review
Proportion of children on ART with HIV‐RNA < 50 copies/ml · HIV‐positive, treatment‐naive children aged one to 12 years old
IMMEDIATE initiation of cART showed no clear difference in proportion of children on ART with HIV‐RNA < 50 copies/ml (Copy) compared with DEFERRED initiation of cART (low certainty).
1 finding from 1 review
Weight gain · HIV‐positive, treatment‐naive children aged one to 12 years old
1 finding from 1 review
Height gain (cm) · HIV‐positive, treatment‐naive children aged one to 12 years old
1 finding from 1 review
Mean standardized score on Beery VMI at 144 weeks · HIV‐positive, treatment‐naive children aged one to 12 years old
1 finding from 1 review
Deep surgical site infection · adults with open long bone fractures of the upper and lower limbs
It is very uncertain whether timing of wound closure (immediate changes deep surgical site infection compared with delayed) (very low certainty).
1 finding from 1 review
Delayed or non‐union (medium term) · adults with open long bone fractures of the upper and lower limbs
It is very uncertain whether timing of wound closure (immediate changes delayed union or non‐union compared with delayed) (very low certainty).
1 finding from 1 review
Unplanned operations at 12 months · adults with open long bone fractures of the upper and lower limbs
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events ‐ superficial infection · adults with open long bone fractures of the upper and lower limbs
It is very uncertain whether timing of wound closure (immediate changes adverse events ‐ superficial infection compared with delayed) (very low certainty).
1 finding from 1 review
Return to work · adults with open long bone fractures of the upper and lower limbs
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Limb function at 6 or 12 months · adults with open long bone fractures of the upper and lower limbs
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
HRQoL at 6 or 12 months · adults with open long bone fractures of the upper and lower limbs
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found