Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

660 questions · 679 findings · 99 reviews · Headline outcomes only

No studies found 160 · 23.6%GRADE not reported 17 · 2.5%Very low 199 · 29.3%Low 189 · 27.8%Moderate 97 · 14.3%High 17 · 2.5%

Transarterial embolisation plus percutaneous alcohol injection vs percutaneous alcohol injection

Cancer‐related mortality at maximal · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

It is very uncertain whether transarterial embolisation plus percutaneous alcohol injection changes cancer‐related mortality at maximal compared with percutaneous alcohol injection (very low certainty).

1 finding from 1 review

Transarterial embolisation plus percutaneous alcohol injection vs percutaneous alcohol injection

Serious adverse events (number of participants) · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

It is very uncertain whether transarterial embolisation plus percutaneous alcohol injection changes serious adverse events (number of participants) compared with percutaneous alcohol injection (very low certainty).

1 finding from 1 review

Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection)

Severe postpartum haemorrhage · pregnant women giving birth in non‐facility settings

It is very uncertain whether prophylactic oxytocin injection (delivered by community health… changes severe postpartum haemorrhage (> 1000 mL) [ compared with control (no injection) (very low certainty).

1 finding from 1 review

Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection)

Postpartum haemorrhage · pregnant women giving birth in non‐facility settings

Prophylactic oxytocin injection (delivered by community health… may leads to lower postpartum haemorrhage (PPH greater or equal to 500 mL) [ compared with control (no injection) (low certainty).

2 findings from 1 review

Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection)

Maternal transfer or referral to a health facility · pregnant women giving birth in non‐facility settings

Prophylactic oxytocin injection (delivered by community health… showed no clear difference in transfer or referral to health facility [ compared with control (no injection) (low certainty).

1 finding from 1 review

Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection)

Stillbirth · pregnant women giving birth in non‐facility settings

Prophylactic oxytocin injection (delivered by community health… showed no clear difference in stillbirths [ compared with control (no injection) (low certainty).

1 finding from 1 review

Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection)

Early infant death (0‐3 days) [ · pregnant women giving birth in non‐facility settings

Prophylactic oxytocin injection (delivered by community health… showed no clear difference in early infant death (0‐3 days) [ compared with control (no injection) (low certainty).

1 finding from 1 review

Embryo culture supernatant injection vs no intervention

Live birth or ongoing pregnancy · Subfertile women undergoing assisted reproduction

It is very uncertain whether embryo culture supernatant injection changes live birth/ongoing pregnancy compared with no intervention (very low certainty).

1 finding from 1 review