Cochrane · systematic review · CD011491
Oxytocin for preventing postpartum haemorrhage (PPH) in non‐facility birth settings
Pantoja, T, Abalos, E, Chapman, E, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
8
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 37.5%Low 5 · 62.5%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Prophylactic oxytocin injection (delivered by community health officer) versus control (no injection) for preventing postpartum haemorrhage
Population: pregnant women giving birth in non‐facility settings
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Severe postpartum haemorrhage (> 1000 mL) [ Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection) | RR 0.16 [0.02, 1.3] | 1 study · 1569 participants | Very low Downgraded: risk of bias, imprecision |
Severe maternal morbidity Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection) | no estimate extracted | 1 study · 1586 participants | Very low Downgraded: risk of bias, imprecision |
Maternal deaths Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection) | no estimate extracted | 1 study · 1586 participants | Very low Downgraded: risk of bias, imprecision |
Postpartum haemorrhage (PPH greater or equal to 500 mL) [ Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection) | RR 0.48 [0.28, 0.81] | 1 study · 1574 participants | Low Downgraded: risk of bias, imprecision |
Postpartum haemorrhage (adjusted by design effect) [ Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection) | RR 0.49 [0.27, 0.9] | 1 study · 1574 participants | Low Downgraded: risk of bias, imprecision |
Transfer or referral to health facility [ Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection) | RR 0.72 [0.34, 1.56] | 1 study · 1586 participants | Low Downgraded: risk of bias, imprecision |
Stillbirths [ Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection) | RR 1.27 [0.67, 2.4] | 1 study · 2006 participants | Low Downgraded: risk of bias, imprecision |
Early infant death (0‐3 days) [ Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection) | RR 1.03 [0.35, 3.07] | 1 study · 1969 participants | Low Downgraded: risk of bias, imprecision |