Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

374 questions · 393 findings · 47 reviews · Headline outcomes only

No studies found 73 · 18.6%GRADE not reported 16 · 4.1%Very low 164 · 41.7%Low 85 · 21.6%Moderate 36 · 9.2%High 19 · 4.8%

Prophylactic antibiotics vs placebo or no treatment

Mesh exposure · women with urinary stress incontinence undergoing continence surgery

It is very uncertain whether prophylactic antibiotics (single or combined drugs) changes number of mesh exposures within six weeks after the operation compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Intervention not reported

Cohort studies postexposure prophylaxis · children 9 months to 15 years old

The intervention may leads to lower cohort studies postexposure prophylaxis (low certainty).

1 finding from 1 review

Standard treatment plus systemic corticosteroids vs usual care

Adverse effects: exposure keratopathy · patients age 10 years and older with periorbital or orbital cellulitis

It is very uncertain whether standard treatment plus systemic corticosteroids changes adverse effects: exposure keratopathy compared with standard treatment alone (very low certainty).

1 finding from 1 review

Adalimumab vs placebo

Failure to maintain clinical or endoscopic response with prior TNF‐α antagonist exposure · Participants with Crohn's disease in remission

Adalimumab probably leads to lower failure to maintain clinical or endoscopic response with prior TNF‐α… compared with placebo (moderate certainty).

1 finding from 1 review

Intervention not reported

Re‐exposure to IPV score Scales: Revised Conflict Tactics Scales, Composite Abuse Scale Direction: lower better · women aged 16 years and older who self‐report previous or current experience of intimate partner violence
1 finding from 1 review

Biomedical risk assessment vs Control (waitlist, routine/standard oral health education, or minimal intervention)

Smoking cessation · people who smoke

Biomedical risk assessment showed no clear difference in feedback on smoking exposure Smoking cessation at longest compared with standard care or minimal intervention (moderate certainty).

1 finding from 1 review

Anterior prolapse repair: native tissue vs polypropylene mesh

Repeat surgery ‐ surgery for prolapse, SUI, or mesh exposure review 1 to 3 years · women with anterior compartment pelvic organ prolapse

Anterior prolapse repair: native tissue probably leads to lower repeat surgery for prolapse, SUI or mesh exposure (1‐3 years) compared with polypropylene mesh (moderate certainty).

1 finding from 1 review

Intervention not reported

Proportion of successful procedures at 1 year and up to 5 years after surgery (no exposure/extrusion) · people with anophthalmic sockets

The intervention showed no clear difference in proportion of successful procedures at 1 year and up to 5 years… (low certainty).

1 finding from 1 review

Intervention not reported

Co‐operation during induction ‐ Mask introduction/exposure (Mask) ICC (number of children compliant) · children

It is very uncertain whether the intervention changes co‐operation during induction ‐ Mask introduction/exposure (Mask)… (very low certainty).

1 finding from 1 review