Cochrane · systematic review · CD012457
Prophylactic antibiotics for preventing infection after continence surgery in women with stress urinary incontinence
Temtanakitpaisan, T, Buppasiri, P, Lumbiganon, P, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
IncontinenceAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
4
No studies
2
Included studies
NR
No studies 2 · 33.3%Ungraded 0 · 0%Very low 4 · 66.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Prophylactic antibiotics (single or combined drugs) versus placebo or no treatment
Population: women with urinary stress incontinence undergoing continence surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Number of surgical site infections (SSIs) before discharge Prophylactic antibiotics (single or combined drugs) vs placebo or no treatment | RR 0.56 [0.13, 12.35] | 2 studies · 85 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Number of major adverse effects defined by the study, before discharge Prophylactic antibiotics (single or combined drugs) vs placebo or no treatment | no estimate extracted | NR | No studies |
Number of symptomatic UTIs or bacteriuria before discharge Prophylactic antibiotics (single or combined drugs) vs placebo or no treatment | RR 0.84 [0.05, 13.24] | 2 studies · 85 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Number of women with febrile morbidity at hospital discharge Prophylactic antibiotics (single or combined drugs) vs placebo or no treatment | RR 0.08 [0, 1.29] | 2 studies · 85 participants | Very low Downgraded: risk of bias, imprecision |
Number of women with sepsis or bacteraemia at hospital discharge Prophylactic antibiotics (single or combined drugs) vs placebo or no treatment | no estimate extracted | NR | No studies |
Number of mesh exposures within six weeks after the operation Prophylactic antibiotics (single or combined drugs) vs placebo or no treatment | RR 0.32 [0.01, 7.61] | 1 study · 59 participants | Very low Downgraded: risk of bias, imprecision |