Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

351 questions · 368 findings · 41 reviews · Headline outcomes only

No studies found 47 · 12.8%GRADE not reported 16 · 4.3%Very low 68 · 18.5%Low 92 · 25%Moderate 97 · 26.4%High 48 · 13%

Manual therapy and exercise vs glucocorticoid injection

Global assessment of treatment success · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy and exercise probably leads to lower global assessment of treatment success Complete recovery or much… compared with glucocorticoid injection (moderate certainty).

1 finding from 1 review

Monotherapy vs combination therapy

Clinical cure · Ventilator‐associated pneumonia

It is very uncertain whether monotherapy changes clinical cure (ITT) compared with combination therapy (very low certainty).

2 findings from 1 review