Clinical response: No clinically important response ‐ as defined by each of the studies · schizophrenia or related disorders
It is very uncertain whether combinations of antipsychotic drugs changes clinical response: No clinically important response ‐ as defined by… compared with single antipsychotic drugs (very low certainty).
1 finding from 1 review
Relapse · schizophrenia or related disorders
1 finding from 1 review
Leaving the study early · schizophrenia or related disorders
Combinations of antipsychotic drugs showed no clear difference in leaving the study early compared with single antipsychotic drugs (low certainty).
1 finding from 1 review
Hospital admissions · schizophrenia or related disorders
It is very uncertain whether combinations of antipsychotic drugs changes service utilisation: Hospital admission compared with single antipsychotic drugs (very low certainty).
1 finding from 1 review
Service utilisation: Change in hospital status ‐ not reported · schizophrenia or related disorders
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events: Serious event or requiring discontinuation · schizophrenia or related disorders
It is very uncertain whether combinations of antipsychotic drugs changes adverse events: Serious event or requiring discontinuation compared with single antipsychotic drugs (very low certainty).
1 finding from 1 review
Quality of life · schizophrenia or related disorders
1 finding from 1 review
Participant‐reported pain relief of 30% or greater · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Participant‐reported pain relief of 50% or greater · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Patient Global Impression of Change much or very much improved · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Any pain‐related outcome indicating some improvement · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Number experiencing adverse effects · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Number of participants experiencing any serious adverse events · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Withdrawals due to adverse events · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Withdrawals due to adverse events · people with primary hypertension
1 finding from 1 review
Total mortality · people with primary hypertension
It is very uncertain whether combination with potassium‐sparing diuretics changes total mortality compared with monotherapy (very low certainty).
1 finding from 1 review
Cardiovascular mortality · people with primary hypertension
1 finding from 1 review
Cardiovascular events · people with primary hypertension
It is very uncertain whether combination with potassium‐sparing diuretics changes cardiovascular events compared with monotherapy (very low certainty).
1 finding from 1 review
Serious adverse events · people with primary hypertension
It is very uncertain whether combination with potassium‐sparing diuretics changes serious adverse events compared with monotherapy (very low certainty).
1 finding from 1 review
Tinnitus symptom severity · adults with subjective idiopathic tinnitus
1 finding from 1 review