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What do systematic reviews say?

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Evidence found and GRADE certainty

1,005 questions · 1,053 findings · 151 reviews · Headline outcomes only

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No studies found 275 · 26.1%GRADE not reported 150 · 14.2%Very low 271 · 25.7%Low 215 · 20.4%Moderate 105 · 10%High 37 · 3.5%

Early intervention (mobilization or active exercise) vs usual care

Adverse events Proportion of participants with one or more events, or proportion of intervention sessions where an event occurred (falls, accidental dislodgement of attachments, haemodynamic instability, oxygen desaturation or any other adverse ev... · critically ill, mechanically ventilated adults
1 finding from 1 review

Visual interventions vs control

Activities of daily living · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

It is very uncertain whether visual interventions changes activities of daily living: effects persisting at least 1 month post… compared with any control (very low certainty).

2 findings from 1 review

Visual interventions vs control

Neglect outcomes: effects persisting at least 1 month post intervention · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

It is very uncertain whether visual interventions changes neglect outcomes: effects persisting at least 1 month post… compared with any control (very low certainty).

1 finding from 1 review

Psychological interventions vs treatment

Acceptability · adults with long‐term physical conditions (18 years or older)

Psychological interventions may leads to higher acceptability ‐ drop‐outs due to any cause: post‐intervention compared with treatment (low certainty).

2 findings from 1 review

Any supplements containing iron vs same supplements without iron or no treatment/placebo (no iron or placebo)

Side effects (any reported throughout the intervention period) (ALL) · pregnant women

It is very uncertain whether (Maternal outcomes) Any supplements containing iron changes side effects (any reported throughout the intervention period) (ALL) compared with same supplements without iron or no treatment/placebo (no iron or… (very low certainty).

1 finding from 1 review

Movement interventions vs control

Activities of daily living · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

The review found no eligible studies for this question.

2 findings from 1 review

Movement interventions vs control

Neglect outcomes: effects persisting at least 1 month post intervention · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

The review found no eligible studies for this question.

1 finding from 1 review

Any supplements containing iron and folic acid vs same supplements without iron nor folic acid (no iron nor folic acid or placebo)

Side effects (any reported throughout the intervention period) (ALL) · pregnant women

(Maternal outcomes) Any supplements containing iron and folic acid probably leads to higher side effects (any reported throughout the intervention period) (ALL) compared with same supplements without iron nor folic acid (no iron nor folic acid… (moderate certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Acceptability · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes acceptability ‐ drop‐outs due to any cause: post‐intervention compared with placebo (very low certainty).

2 findings from 1 review