Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

80 questions · 82 findings · 10 reviews

No studies found 13 · 15.9%GRADE not reported 12 · 14.6%Very low 23 · 28%Low 25 · 30.5%Moderate 9 · 11%High 0 · 0%

Intervention not reported

Proportion of patients who are seizure free at 3 months · Patients between three and 12 years old with clinical and EEG diagnosis of BECTS

It is very uncertain whether the intervention changes proportion of patients who are seizure free at 3 months (very low certainty).

1 finding from 1 review

Intervention not reported

Proportion of patients who are seizure free at 12 months · Patients between three and 12 years old with clinical and EEG diagnosis of BECTS

It is very uncertain whether the intervention changes proportion of patients who are seizure free at 12 months (very low certainty).

1 finding from 1 review

Intervention not reported

Proportion of patients who discontinued treatment due to adverse events ( · Patients between three and 12 years old with clinical and EEG diagnosis of BECTS

The intervention showed no clear difference in proportion of patients who discontinued treatment due to adverse… (low certainty).

1 finding from 1 review

Tizanidine vs carbamazepine

Immediate improvement in pain relief Number of participants improved (good/very good efficacy) on a self assessed categorical 'overall efficacy score' (0 = no efficacy to 4 = very good) · patients with trigeminal neuralgia

Tizanidine showed no clear difference in immediate improvement in pain relief Number of participants improved… compared with carbamazepine (low certainty).

1 finding from 1 review