Proparacaine hydrochloride 0.5% eye drops vs placebo: Relief of pain
Proparacaine hydrochloride 0.5% eye drops showed no clear difference in immediate improvement in pain relief Number of participants improved… compared with placebo (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Proparacaine hydrochloride 0.5% eye drops vs placebo Immediate improvement in pain relief Number of participants improved (≥ 2 level decrease in pain on 10‐point verbal rating scale, or pain gone or rare) · patients with trigeminal neuralgia Proparacaine hydrochloride 0.5% eye drops showed no clear difference in immediate improvement in pain relief Number of participants improved… compared with placebo (low certainty). Non‐antiepileptic drugs for trigeminal neuralgia (2013) · Cochrane Headline outcomes only | RR 1.06 [0.37, 2.99] | 1 study · 47 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Non‐antiepileptic drugs for trigeminal neuralgia 2013 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.