Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

897 questions · 966 findings · 73 reviews

No studies found 269 · 27.8%GRADE not reported 101 · 10.5%Very low 284 · 29.4%Low 180 · 18.6%Moderate 107 · 11.1%High 25 · 2.6%

Clonidine vs placebo

ADHD symptom‐related behavior Measured by standardized rating scales: Conners' Abbreviated Teacher Rating Scale, Conners' Abbreviated Parent Rating Scale, IOWA Conners' Teacher Rating Scale, Conners' Continuous Performance Task, Child Behaviour Ch... · children with ADHD and comorbid tic disorders
1 finding from 1 review

Desipramine (antidepressant) vs placebo

ADHD symptom‐related behavior Measured by standardized rating scales: Child Behaviour Checklist, Gordon Diagnostic System, Clinical Evaluation of Language Function, Matching Familial Figures Test, Porteus Maze Test, Restricted Academic Test, ADHD ... · children with ADHD and comorbid tic disorders
1 finding from 1 review

Desipramine (antidepressant) vs placebo

Tic severity Measured by standardized rating scales: Yale Global Tic Severity Scale, Tourette Syndrome Severity Scale, Hopkins Motor/Vocal Scale; ADHD Parent Linear Analogue Scale · children with ADHD and comorbid tic disorders
1 finding from 1 review

Metoprolol vs placebo

All cardiovascular death · patients of any age with AAA less than 30 mm in diameter

Metoprolol showed no clear difference in cardiovascular death, 30 days3 compared with placebo (low certainty).

2 findings from 1 review