Cochrane · systematic review · CD010447
Pharmacological treatment of vascular risk factors for reducing mortality and cardiovascular events in patients with abdominal aortic aneurysm
Robertson, L, Atallah, E, Stansby, G · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
VascularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
7
No studies
1
Included studies
NR
No studies 1 · 12.5%Ungraded 0 · 0%Very low 0 · 0%Low 7 · 87.5%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Metoprolol compared to placebo for reducing mortality and cardiovascular events in patients with abdominal aortic aneurysm
Population: patients of any age with AAA less than 30 mm in diameter
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality, 30 days1 Metoprolol vs placebo | OR 0.17 [0.02, 1.41] | 1 study · 227 participants | Low Downgraded: imprecision |
Cardiovascular death, 30 days3 Metoprolol vs placebo | OR 0.2 [0.02, 1.76] | 1 study · 227 participants | Low Downgraded: imprecision |
AAA‐related death, 30 days4 Metoprolol vs placebo | OR 1.05 [0.06, 16.92] | 1 study · 227 participants | Low Downgraded: imprecision |
Nonfatal cardiovascular event, 30 days5 Metoprolol vs placebo | OR 1.44 [0.58, 3.57] | 1 study · 227 participants | Low Downgraded: imprecision |
All‐cause mortality, 6 months1 Metoprolol vs placebo | OR 0.71 [0.26, 1.95] | 1 study · 227 participants | Low Downgraded: imprecision |
Cardiovascular death, 6 months3 Metoprolol vs placebo | OR 0.73 [0.23, 2.39] | 1 study · 227 participants | Low Downgraded: imprecision |
AAA‐related death, 6 months4 Metoprolol vs placebo | no estimate extracted | NR | No studies |
Nonfatal cardiovascular event, 6 months5 Metoprolol vs placebo | OR 1.41 [0.59, 3.35] | 1 study · 227 participants | Low Downgraded: imprecision |