Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,771 questions · 10,185 findings · 893 reviews

No studies found 2,109 · 20.7%GRADE not reported 1,125 · 11%Very low 2,279 · 22.4%Low 2,514 · 24.7%Moderate 1,709 · 16.8%High 449 · 4.4%

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Radiotherapy vs botulinum toxin

Reduction in the amount of saliva production in the short term using an objective measure · sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis

The review found no eligible studies for this question.

1 finding from 1 review

Radiotherapy vs botulinum toxin

Adverse events, reported as "negative experiences" · sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis

It is very uncertain whether radiotherapy changes adverse events, reported as "negative experiences" compared with botulinum toxin (very low certainty).

1 finding from 1 review

Radiotherapy vs surgical excision

Recurrence · adults with basal cell carcinoma of the skin

Radiotherapy may leads to higher recurrence at 3 years compared with surgical excision (with or without frozen section margin control) (low certainty).

2 findings from 1 review

Radiotherapy vs surgical excision

Cosmetic outcome (good/excellent) · adults with basal cell carcinoma of the skin

Radiotherapy probably leads to lower cosmetic outcome (good/excellent) compared with surgical excision (with or without frozen section margin control) (moderate certainty).

1 finding from 1 review

Phytotherapy vs Another topical agent or placebo

Prostatitis symptoms: 'responders' Number of participants with a 25% or 6‐point decrease in NIH‐CPSI scores · participants with chronic prostatitis/chronic pelvic pain syndrome

Phytotherapy probably leads to higher prostatitis symptoms: 'responders' Number of participants with a 25%… compared with placebo or other agents (moderate certainty).

1 finding from 1 review