Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

821 questions · 842 findings · 96 reviews

No studies found 275 · 32.7%GRADE not reported 88 · 10.5%Very low 197 · 23.4%Low 187 · 22.2%Moderate 86 · 10.2%High 9 · 1.1%

Cannabidiol vs placebo

Withdrawals due to adverse events · people with active UC

Cannabidiol showed no clear difference in withdrawal due to adverse event compared with placebo (low certainty).

1 finding from 1 review

Open reduction and fixation vs Closed (conservative) management (no active intervention other than soft diet, analgesics or antibiotics; or intermaxillary/maxillary-mandibular fixation with rigid or elastic traction)

Outcome not reported · Adults, over 18 years of age, with unilateral or bilateral fractures of the mandibular condyles

The review found no eligible studies for this question.

1 finding from 1 review

Manipulation vs mobilisation

Acute, subacute and chronic neck pain Intermediate‐term · patients with acute, subacute and chronic neck pain

Manipulation showed no clear difference in acute, subacute and chronic neck pain Intermediate‐term compared with mobilisation (moderate certainty).

1 finding from 1 review

Manipulation (cervical) vs oral medicine

Acute and subacute neck pain Intermediate‐term · patients with acute and subacute neck pain

Manipulation (cervical) showed no clear difference in acute and subacute neck pain Intermediate‐term compared with oral medicine (moderate certainty).

1 finding from 1 review