Cochrane · systematic review · CD007744

Tolerability of selective cyclooxygenase 2 inhibitors used for the treatment of rheumatological manifestations of inflammatory bowel disease

Miao, XP, Li, JS, Ouyang, Q, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 100%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Etoricoxib versus placebo for treatment of rheumatological manifestations of inflammatory bowel disease

Population: patients with active or quiescent IBD
1 question
OutcomeEffectEvidenceStatus / GRADE
Exacerbation of IBD
Etoricoxib vs placebo
RR 0.88 [0.45, 1.69]1 study · 159 participantsLow
Downgraded: imprecision

Celecoxib versus placebo for treatment of rheumatological manifestations of ulcerative colitis

Population: patients with quiescent ulcerative colitis
2 questions
OutcomeEffectEvidenceStatus / GRADE
Exacerbation of ulcerative colitis
Celecoxib vs placebo
RR 0.7 [0.23, 2.14]1 study · 222 participantsLow
Downgraded: imprecision
GI adverse events
Celecoxib vs placebo
RR 0.97 [0.46, 2.07]1 study · 221 participantsLow
Downgraded: imprecision