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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,956 questions in 143 reviews · Musculoskeletal
current versionsNo studies 555 · 28.4%Ungraded 107 · 5.5%Very low 255 · 13%Low 555 · 28.4%Moderate 357 · 18.3%High 127 · 6.5%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intervention NR Number of patients experiencing any adverse event · Patients with knee osteoarthritis (none of the trials included patients with hip osteoarthritis) Therapeutic ultrasound for osteoarthritis of the knee or hip (2010) · Cochrane | no estimate extracted | 1 study · 67 participants | Low |
Intervention NR Number of patients who withdrew because of adverse events · Patients with knee osteoarthritis (none of the trials included patients with hip osteoarthritis) Therapeutic ultrasound for osteoarthritis of the knee or hip (2010) · Cochrane | no estimate extracted | 1 study · 67 participants | Low |
Intervention NR Number of patients experiencing any serious adverse event · Patients with knee osteoarthritis (none of the trials included patients with hip osteoarthritis) Therapeutic ultrasound for osteoarthritis of the knee or hip (2010) · Cochrane | no estimate extracted | 2 studies · 136 participants | Low |
Augmented subscapularis transposition vs subscapularis transposition alone during total shoulder arthroplasty Pain The Hospital for Special Surgrery 100‐point scoring system. Scale from: 0 to 30 (higher is better). · Patients with rheumatoid shoulder Surgical interventions for the rheumatoid shoulder (2010) · Cochrane | no estimate extracted | 1 study · 39 participants | Low |
Augmented subscapularis transposition vs subscapularis transposition alone during total shoulder arthroplasty Function The Hospital for Special Surgery 100‐point scoring system. Scale from: 0 to 20 (higher is better). · Patients with rheumatoid shoulder Surgical interventions for the rheumatoid shoulder (2010) · Cochrane | no estimate extracted | 1 study · 39 participants | Low |
Augmented subscapularis transposition vs subscapularis transposition alone during total shoulder arthroplasty Quality of life ‐ not reported · Patients with rheumatoid shoulder Surgical interventions for the rheumatoid shoulder (2010) · Cochrane | no estimate extracted | NR | No studies |
Augmented subscapularis transposition vs subscapularis transposition alone during total shoulder arthroplasty Range of motion The Hospital for Special Surgery 100‐point scoring system . Scale from: 0 to 25 (higher is better). · Patients with rheumatoid shoulder Surgical interventions for the rheumatoid shoulder (2010) · Cochrane | no estimate extracted | 1 study · 39 participants | Low |
Augmented subscapularis transposition vs subscapularis transposition alone during total shoulder arthroplasty Infections · Patients with rheumatoid shoulder Surgical interventions for the rheumatoid shoulder (2010) · Cochrane | OR 0.13 [0, 6.48] | 1 study · 39 participants | Low |
Augmented subscapularis transposition vs subscapularis transposition alone during total shoulder arthroplasty Component loosening / revisions ‐ not reported · Patients with rheumatoid shoulder Surgical interventions for the rheumatoid shoulder (2010) · Cochrane | no estimate extracted | NR | No studies |
Augmented subscapularis transposition vs subscapularis transposition alone during total shoulder arthroplasty Other complications ‐ not reported · Patients with rheumatoid shoulder Surgical interventions for the rheumatoid shoulder (2010) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR % Change total body bone mineral content from baseline · patients with improving bone mineral density in children Vitamin D supplementation for improving bone mineral density in children (2010) · Cochrane | no estimate extracted | 5 studies · 672 participants | High |
Intervention NR % Change hip bone mineral density from baseline · patients with improving bone mineral density in children Vitamin D supplementation for improving bone mineral density in children (2010) · Cochrane | no estimate extracted | 4 studies · 639 participants | Moderate |
Intervention NR % Change lumbar spine bone mineral density from baseline · patients with improving bone mineral density in children Vitamin D supplementation for improving bone mineral density in children (2010) · Cochrane | no estimate extracted | 5 studies · 660 participants | High |
Intervention NR % Change forearm bone mineral density from baseline · patients with improving bone mineral density in children Vitamin D supplementation for improving bone mineral density in children (2010) · Cochrane | no estimate extracted | 3 studies · 427 participants | Moderate |
Intervention NR Adverse events3 ‐ not reported · patients with improving bone mineral density in children Vitamin D supplementation for improving bone mineral density in children (2010) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Function Scales: Timed up and go test, Functional stair test and Nottingham health profile · for quadriceps strengthening pre and post total knee replacement Surface neuromuscular electrical stimulation for quadriceps strengthening pre and post total knee replacement (2010) · Cochrane | no estimate extracted | 0 studies · 2 participants | Ungraded |
Intervention NR Patient Satisfaction ‐ not measured · for quadriceps strengthening pre and post total knee replacement Surface neuromuscular electrical stimulation for quadriceps strengthening pre and post total knee replacement (2010) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Pain ‐ not measured · for quadriceps strengthening pre and post total knee replacement Surface neuromuscular electrical stimulation for quadriceps strengthening pre and post total knee replacement (2010) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Quadriceps strength · for quadriceps strengthening pre and post total knee replacement Surface neuromuscular electrical stimulation for quadriceps strengthening pre and post total knee replacement (2010) · Cochrane | no estimate extracted | 0 studies · 2 participants | Ungraded |
Intervention NR Quadriceps activation · for quadriceps strengthening pre and post total knee replacement Surface neuromuscular electrical stimulation for quadriceps strengthening pre and post total knee replacement (2010) · Cochrane | no estimate extracted | 1 study · 34 participants | Ungraded |
Intervention NR Adverse effects ‐ burns, skin damage, or cardiac arrhythmias ‐ not measured · for quadriceps strengthening pre and post total knee replacement Surface neuromuscular electrical stimulation for quadriceps strengthening pre and post total knee replacement (2010) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Pain intensity Various validated pain scales · Patients with osteoarthritis of the knee Joint lavage for osteoarthritis of the knee (2010) · Cochrane | no estimate extracted | 7 studies · 567 participants | Low |
Intervention NR Pain intensity Various validated pain scales · Patients with osteoarthritis of the knee Joint lavage for osteoarthritis of the knee (2010) · Cochrane | no estimate extracted | 3 studies · 380 participants | Low |
Intervention NR Function Various validated function scales. · Patients with osteoarthritis of the knee Joint lavage for osteoarthritis of the knee (2010) · Cochrane | no estimate extracted | 5 studies · 540 participants | Low |
Intervention NR Function Various validated function scales. · Patients with osteoarthritis of the knee Joint lavage for osteoarthritis of the knee (2010) · Cochrane | no estimate extracted | 3 studies · 381 participants | Low |
Intervention NR Number of patients experiencing adverse events · Patients with osteoarthritis of the knee Joint lavage for osteoarthritis of the knee (2010) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Number of patients who withdrew due to adverse event · Patients with osteoarthritis of the knee Joint lavage for osteoarthritis of the knee (2010) · Cochrane | no estimate extracted | 1 study · 8 participants | Very low |
Intervention NR Number of patients experiencing any serious adverse event · Patients with osteoarthritis of the knee Joint lavage for osteoarthritis of the knee (2010) · Cochrane | no estimate extracted | 1 study · 98 participants | Very low |
Intervention NR ACR‐50 · patients with rheumatoid arthritis Balance training (proprioceptive training) for patients with rheumatoid arthritis (2010) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Pain · patients with rheumatoid arthritis Balance training (proprioceptive training) for patients with rheumatoid arthritis (2010) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR DAS (low or remission) · patients with rheumatoid arthritis Balance training (proprioceptive training) for patients with rheumatoid arthritis (2010) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR HAQ for function · patients with rheumatoid arthritis Balance training (proprioceptive training) for patients with rheumatoid arthritis (2010) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Gait · patients with rheumatoid arthritis Balance training (proprioceptive training) for patients with rheumatoid arthritis (2010) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Adverse effects · patients with rheumatoid arthritis Balance training (proprioceptive training) for patients with rheumatoid arthritis (2010) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Discontinuation rates · patients with rheumatoid arthritis Balance training (proprioceptive training) for patients with rheumatoid arthritis (2010) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Pain level Verbal pain scale. Scale from: 0 to 10. ( · patients with big toe joint osteoarthritis Interventions for treating osteoarthritis of the big toe joint (2010) · Cochrane | no estimate extracted | 1 study · 20 participants | Low |
Intervention NR Physical Function ‐ not measured · patients with big toe joint osteoarthritis Interventions for treating osteoarthritis of the big toe joint (2010) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Adverse effects ( · patients with big toe joint osteoarthritis Interventions for treating osteoarthritis of the big toe joint (2010) · Cochrane | no estimate extracted | NR | No studies |
Total Shoulder Arthroplasty vs Hemiarthroplasty Pain (Visual Analog Scale) Visual Analog Scale. Scale from: 0 to 100 (Lower is better). · patients with Shoulder osteoarthritis Surgery for shoulder osteoarthritis (2010) · Cochrane | no estimate extracted | 1 study · 41 participants | Low |
Total Shoulder Arthroplasty vs Hemiarthroplasty Disability/Function (ASES) American Shoulder and Elbow Surgeons Shoulder Score. Scale from: 0 to 100 (Higher is better). · patients with Shoulder osteoarthritis Surgery for shoulder osteoarthritis (2010) · Cochrane | no estimate extracted | 2 studies · 88 participants | Moderate |
Total Shoulder Arthroplasty vs Hemiarthroplasty Adverse Events‐Total (Intra‐operative and post‐operative) · patients with Shoulder osteoarthritis Surgery for shoulder osteoarthritis (2010) · Cochrane | RR 1.19 [0.37, 3.81] | 1 study · 41 participants | Moderate |
Total Shoulder Arthroplasty vs Hemiarthroplasty Revision Rate · patients with Shoulder osteoarthritis Surgery for shoulder osteoarthritis (2010) · Cochrane | RR 6.18 [0.77, 49.52] | 2 studies · 88 participants | Moderate |
Total Shoulder Arthroplasty vs Hemiarthroplasty Serious Adverse Events4 · patients with Shoulder osteoarthritis Surgery for shoulder osteoarthritis (2010) · Cochrane | no estimate extracted | 0 studies · 5 participants | Ungraded |
Total Shoulder Arthroplasty vs Hemiarthroplasty Withdrawals due to adverse event · patients with Shoulder osteoarthritis Surgery for shoulder osteoarthritis (2010) · Cochrane | no estimate extracted | 0 studies · 5 participants | Ungraded |
Intervention NR Pain (0‐10 cm visual analog scale)‐ Pain at 6‐12 weeks Visual Analog or Verbal Rating Scale. Scale from: 0 to 10. ( · patients with shoulder pain Botulinum toxin for shoulder pain (2010) · Cochrane | no estimate extracted | 3 studies · 76 participants | Low |
Intervention NR Number of Adverse Events (AEs) ( · patients with shoulder pain Botulinum toxin for shoulder pain (2010) · Cochrane | RR 1.46 [0.64, 3.36] | 3 studies · 65 participants | Low |
Intervention NR Disability/function ‐ not reported · patients with shoulder pain Botulinum toxin for shoulder pain (2010) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR WIthdrawals due to Adverse Events ‐ not reported · patients with shoulder pain Botulinum toxin for shoulder pain (2010) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Serious Adverse Events ‐ not reported · patients with shoulder pain Botulinum toxin for shoulder pain (2010) · Cochrane | no estimate extracted | NR | No studies |
Tocilizumab 8 mg/kg + MTX/DMARD vs placebo + MTX/DMARD ACR50% improvement criteria · patients with rheumatoid arthritis Tocilizumab for rheumatoid arthritis (2010) · Cochrane | RR 3.17 [2.72, 3.67] | 4 studies · 2063 participants | High |