All‐cause mortality · people with leptospirosis
It is very uncertain whether summary of findings table ‐ Antibiotics changes all‐cause mortality compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Serious adverse event ‐ not reported · people with leptospirosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events considered non‐serious · people with leptospirosis
It is very uncertain whether summary of findings table ‐ Antibiotics changes adverse events considered non‐serious compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Cure: short‐term success · patients on maintenance HD with CRBSI
It is very uncertain whether systemic antibiotics plus antibiotic lock solutions plus tissue… changes cure: short‐term success compared with systemic antibiotics plus antibiotic lock solutions plus heparin (very low certainty).
1 finding from 1 review
RR 0.92 [0.74, 1.15]
18 participants
Very low
Cure: long‐term success · patients on maintenance HD with CRBSI
It is very uncertain whether systemic antibiotics plus antibiotic lock solutions plus tissue… changes cure: long‐term success compared with systemic antibiotics plus antibiotic lock solutions plus heparin (very low certainty).
1 finding from 1 review
RR 64 [0.38, 1.06]
18 participants
Very low
Cure: infection‐free survival · patients on maintenance HD with CRBSI
1 finding from 1 review
no estimate extracted
18 participants
Very low
Stenosis or thrombosis of vascular access site after catheter removal · patients on maintenance HD with CRBSI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Death · patients on maintenance HD with CRBSI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects · patients on maintenance HD with CRBSI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · febrile neutropenia
Early discontinuation of antibiotic treatment showed no clear difference in mortality compared with treatment until neutropenia resolution (low certainty).
1 finding from 1 review
Clinical failure · febrile neutropenia
It is very uncertain whether early discontinuation of antibiotic treatment changes clinical failure compared with treatment until neutropenia resolution (very low certainty).
1 finding from 1 review
Bacteraemia · febrile neutropenia
It is very uncertain whether early discontinuation of antibiotic treatment changes any bacteraemia compared with treatment until neutropenia resolution (very low certainty).
1 finding from 1 review
Overall mortality · people with cancer who have febrile neutropenia
Mortality with anti‐gram‐positive antibiotics showed no clear difference in overall mortality compared with placebo (moderate certainty).
1 finding from 1 review
Resolution of VUR · primary VUR
Antibiotic prophylaxis showed no clear difference in resolution of VUR after 1 to 2 years: unit of analysis (children) compared with surveillance or no treatment (low certainty).
1 finding from 1 review
Adverse events · primary VUR
Antibiotic prophylaxis showed no clear difference in adverse events compared with surveillance or no treatment (moderate certainty).
1 finding from 1 review
Microbial resistance to prophylactic drug: unit of analysis (UTI) · primary VUR
Antibiotic prophylaxis probably leads to higher microbial resistance to prophylactic drug: unit of analysis (UTI) compared with surveillance or no treatment (moderate certainty).
1 finding from 1 review
Recurrence of cellulitis · People with recurrent erysipelas or cellulitis
Antibiotic prophylaxis probably leads to lower recurrence of cellulitis compared with no treatment/placebo (moderate certainty).
1 finding from 1 review
Incidence rate of cellulitis · People with recurrent erysipelas or cellulitis
Antibiotic prophylaxis probably leads to lower incidence rate of cellulitis compared with no treatment/placebo (moderate certainty).
1 finding from 1 review
Time to next episode of cellulitis · People with recurrent erysipelas or cellulitis
Antibiotic prophylaxis probably leads to lower time to next episode of cellulitis compared with no treatment/placebo (moderate certainty).
1 finding from 1 review
Hospital admissions · People with recurrent erysipelas or cellulitis
Antibiotic prophylaxis showed no clear difference in hospitalisation compared with no treatment/placebo (low certainty).
1 finding from 1 review