Postoperative complications after perioperative intervention (e.g. wound‐related complications, secondary surgery, cardiopulmonary complications, admission to intensive care) defined by need for treatment · adult surgical patients consuming 3 or more units of alcohol per day
Perioperative alcohol cessation intervention probably leads to lower postoperative complications after perioperative intervention (e.g.… compared with treatment (moderate certainty).
1 finding from 1 review
In‐hospital and 30‐day mortality · adult surgical patients consuming 3 or more units of alcohol per day
Perioperative alcohol cessation intervention showed no clear difference in in‐hospital and 30‐day mortality compared with treatment (low certainty).
1 finding from 1 review
Successful quitters (number of abstainers) at the end of the programme (with or without validation by interview, breath test, or alcohol markers) · adult surgical patients consuming 3 or more units of alcohol per day
Perioperative alcohol cessation intervention probably leads to higher successful quitters (number of abstainers) at the end of the… compared with treatment (moderate certainty).
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults undergoing surgery with general anaesthesia
1 finding from 1 review
Postoperative opioid consumption, 'overall' (MEQ, mg) · adults undergoing surgery with general anaesthesia
1 finding from 1 review
Gastrointestinal recovery · adults undergoing surgery with general anaesthesia
It is very uncertain whether intravenous (IV) lidocaine changes gastrointestinal recovery compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Adverse events (e.g. the number of participants that died, or had arrhythmias, other heart rate disorders, or showed any signs of lidocaine toxicity) · adults undergoing surgery with general anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Nausea · adults undergoing surgery with general anaesthesia
It is very uncertain whether intravenous (IV) lidocaine changes postoperative nausea, 'overall' (0 to 24 h, to 48 h, to 72 h) compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Postoperative opioid consumption, 'overall' (MEQ, mg) · adults undergoing surgery with general anaesthesia
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults undergoing surgery with general anaesthesia
1 finding from 1 review
Gastrointestinal recovery · adults undergoing surgery with general anaesthesia
1 finding from 1 review
Adverse events (e.g. the number of participants that died, or had arrhythmias, other heart rate disorders, or showed any signs of lidocaine toxicity) · adults undergoing surgery with general anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Nausea · adults undergoing surgery with general anaesthesia
1 finding from 1 review
Intervention not reported
Intraoperative pain (reported dichotomous) · adults (aged ≥ 18 years) undergoing ophthalmic surgery under local anaesthetic eye blocks.
The intervention showed no clear difference in intraoperative pain (reported dichotomous) (low certainty).
1 finding from 1 review
Intervention not reported
Intraoperative pain (reported continuous) · adults (aged ≥ 18 years) undergoing ophthalmic surgery under local anaesthetic eye blocks.
1 finding from 1 review
Intervention not reported
Incidence of harm · adults (aged ≥ 18 years) undergoing ophthalmic surgery under local anaesthetic eye blocks.
1 finding from 1 review
Intervention not reported
Participant satisfaction · adults (aged ≥ 18 years) undergoing ophthalmic surgery under local anaesthetic eye blocks.
1 finding from 1 review
Intervention not reported
Surgical satisfaction · adults (aged ≥ 18 years) undergoing ophthalmic surgery under local anaesthetic eye blocks.
1 finding from 1 review
Intervention not reported
Economic outcomes or cost calculations · adults (aged ≥ 18 years) undergoing ophthalmic surgery under local anaesthetic eye blocks.
1 finding from 1 review
Joint pain at rest · adults having abdominal surgery
1 finding from 1 review