Findings

What do systematic reviews say?

1,340 questions · 1,512 findings · 205 reviews

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No studies found 317 · 21%GRADE not reported 358 · 23.7%Very low 356 · 23.5%Low 271 · 17.9%Moderate 173 · 11.4%High 37 · 2.4%

Laparoscopic vs open appendectomy

Return to normal activities (days) · patients with suspected appendicitis

2 findings from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 383 participants
Moderate
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
17 studies · 1653 participants
Low

Laparoscopic vs open appendectomy

Quality of life · patients with suspected appendicitis

The review found no eligible studies for this question.

2 findings from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Laparoscopic vs open appendectomy

Wound infection · patients with suspected appendicitis

Subgroup analysis (publication date) ‐ Laparoscopic probably leads to lower wound infections compared with open appendectomy (moderate certainty).

3 findings from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.37 [0.27, 0.51]
19 studies · 2217 participants
Moderate
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.42 [0.35, 0.51]
63 studies · 7612 participants
Moderate
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.27 [0.14, 0.52]
5 studies · 783 participants
Moderate

Laparoscopic vs open appendectomy

Intra‐abdominal abscess · patients with suspected appendicitis

Subgroup analysis (publication date) ‐ Laparoscopic showed no clear difference in intra‐abdominal abscesses compared with open appendectomy (low certainty).

4 findings from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.82 [0.44, 1.51]
11 studies · 1466 participants
Low
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.45 [0.19, 1.07]
4 studies · 723 participants
Low
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 1.65 [1.12, 2.43]
53 studies · 6677 participants
Moderate

Show 1 more finding

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.54 [0.24, 1.22]
9 studies · 1185 participants
Low

Laparoscopic vs open appendectomy

Return to normal activity · patients with suspected appendicitis

2 findings from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 380 participants
Very low
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 383 participants
Moderate

Laparoscopic vs open appendectomy

Quality of life Scale used: Gastro‐intestinal Quality of Life Index · patients with suspected appendicitis

1 finding from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
2009 participants
Low

Laparoscopic vs open appendectomy

Quality of life Scale used: 1) Gastro‐intestinal Quality of Life Index 2) SF‐36 questionnaire · patients with suspected appendicitis

1 finding from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
2
2009 participants
Low

Laparoscopic vs open appendectomy

Pain (unpleasantness/intensity/palpation) · patients with suspected appendicitis

1 finding from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 61 participants
Low

Laparoscopic vs open appendectomy

Surgical complications ‐ wound infection · patients with suspected appendicitis

Laparoscopic probably leads to lower wound infections (rate) compared with open appendectomy (moderate certainty).

1 finding from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.25 [0.15, 0.42]
10 studies · 1245 participants
Moderate

Summary of findings table ‐ Platelet transfusion vs no platelet transfusion

Major procedure‐related bleeding · thrombocytopenia

1 finding from 1 review

Use of platelet transfusions prior to lumbar punctures or epidural anaesthesia for the prevention of complications in… 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 150 participants
Very low

Summary of findings table ‐ Platelet transfusion vs no platelet transfusion

All‐cause mortality up to 30 days after the procedure · thrombocytopenia

The review found no eligible studies for this question.

1 finding from 1 review

Use of platelet transfusions prior to lumbar punctures or epidural anaesthesia for the prevention of complications in… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Platelet transfusion vs no platelet transfusion

Transfusion‐related complications within 24 hours of the procedure · thrombocytopenia

The review found no eligible studies for this question.

1 finding from 1 review

Use of platelet transfusions prior to lumbar punctures or epidural anaesthesia for the prevention of complications in… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Platelet transfusion vs no platelet transfusion

Procedure‐related (lumbar puncture or epidural anaesthetic) complications within 7 days of the procedure · thrombocytopenia

1 finding from 1 review

Use of platelet transfusions prior to lumbar punctures or epidural anaesthesia for the prevention of complications in… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Very low

Summary of findings table ‐ Platelet transfusion vs no platelet transfusion

Quality of life (as defined by the individual studies) · thrombocytopenia

The review found no eligible studies for this question.

1 finding from 1 review

Use of platelet transfusions prior to lumbar punctures or epidural anaesthesia for the prevention of complications in… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

NPWT 125 mmHg vs usual care

Complete wound healing · open fracture wounds

NPWT 125 mmHg showed no clear difference in complete wound healing compared with standard care (moderate certainty).

1 finding from 1 review

Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
RR 1.01 [0.81, 1.27]
1 study · 460 participants
Moderate

NPWT 125 mmHg vs usual care

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · other open traumatic wounds

1 finding from 1 review

Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 51 participants
Low

NPWT 75 mmHg vs usual care

Complete wound healing · other open traumatic wounds

The review found no eligible studies for this question.

1 finding from 1 review

Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

NPWT 75 mmHg vs usual care

Wound infection · other open traumatic wounds

It is very uncertain whether NPWT 75 mmHg changes wound infection compared with standard care (very low certainty).

1 finding from 1 review

Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
RR 0.44 [0.17, 1.1]
1 study · 463 participants
Very low

NPWT 75 mmHg vs usual care

Adverse events · other open traumatic wounds

The review found no eligible studies for this question.

1 finding from 1 review

Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

NPWT 75 mmHg vs usual care

Time to closure or coverage surgery · other open traumatic wounds

The review found no eligible studies for this question.

1 finding from 1 review

Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found